Results 31 to 40 of about 2,941 (184)

Dental disease in alpacas. Part 1: Prevalence of dental disorders and their mutual relationships

Journal of Veterinary Internal Medicine, 2020
Background Dental disease is a troublesome health concern in alpacas. Specifically, the occurrence of tooth root abscesses has been described in veterinary literature.
Kirsten Proost, Bart Pardon, Elke Pollaris, Thijs Flahou, Lieven Vlaminck   +4 more
doaj   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

A Generalizable Framework for Building Executable Domain‐Specific Large Language Models Under Data Scarcity: Demonstration on Semiconductor Technology Computer‐Aided Design Simulation

Advanced Intelligent Systems, EarlyView.
A schema‐first alignment framework builds compact, executable domain‐specific language models under data scarcity. Large‐scale synthetic question‐answer generation instills domain knowledge, and a code‐centric IR‐to‐DPO pipeline aligns generation with tool‐executable syntax.
Di Wang, Zhenhua Wu, Yu Liu, Kai Chang, Shaohua Wu   +4 more
wiley   +1 more source

Morphological adaptations of cervical vertebrae in plunge‐diving sulids

The Anatomical Record, EarlyView.
Abstract Foraging strategy frequently drives morphological diversification in birds. The plunge‐diving behavior of certain species makes the functional and ecological trade‐offs of variation in cervical vertebrae an especially intriguing question. This study compares cervical vertebrae across five plunge‐diving species and two non‐plunge‐diving species,
Megan L. Vandenberg, Alissa Perez, John Michael Racy, Adam P. Summers, Ed Habtour, Bart Boom   +5 more
wiley   +1 more source

Divergent Genotype of Hepatitis A Virus in Alpacas, Bolivia, 2019

Emerging Infectious Diseases, 2023
Hepatitis A virus (HAV) is a common human pathogen found exclusively in primates. In a molecular and serologic study of 64 alpacas in Bolivia, we detected RNA of distinct HAV in ≈9% of animals and HAV antibodies in ≈64%.
Talitha Veith, L. Fabian Beltran-Saavedra, Tobias Bleicker, Marie Luisa Schmidt, José L. Mollericona, Kim Grützmacher, Rob Wallace, Jan Felix Drexler, Christian Walzer, Terry C. Jones, Christian Drosten, Victor Max Corman   +11 more
doaj   +1 more source

Transition Metal Compounds as Thermochromic Materials: Classification, Properties, Limitations, and Applications

EcoEnergy, EarlyView.
This review systematically examines how different transition metal compounds—such as binary and multinary metal oxides, halides, sulfides, and salts—exhibit thermochromism based on the d‐electron configurations of their transition metal cations. It focuses on three main mechanisms of thermochromism: phase transition, charge transfer, and bandgap change.
Jie Wang, Shan Wang, Long Yuan, Ling Zuo, Hui Qi, Changmin Hou   +5 more
wiley   +1 more source

Disease of South American camelids in England and Wales: Analysis of diagnoses from Animal and Plant Health Agency laboratory submissions between 2012 and 2021

Veterinary Record, EarlyView.
Abstract Background South American camelids (SACs) have become increasingly popular in the UK. Consequently, knowledge among veterinary practitioners about diseases in these non‐native species has improved, although gaps remain. The remit of this study was to identify common diseases of SACs based on Animal and Plant Health Agency (APHA) surveillance ...
Sonja Jeckel, Carissa Xian Chow, David Jorge   +2 more
wiley   +1 more source

Using Real-Time GNSS Tracking Tags to Monitor Alpaca Activity in an Australian Extensive Production System

Agriculture
Australian alpacas contribute to a developing alternative fibre industry with an increasing number of larger-scale enterprises requiring real-time management options.
Imogen Boughey, Evelyn Hall, Russell Bush   +2 more
doaj   +1 more source

A Literature Review of Selected Bacterial Diseases in Alpacas and Llamas—Epidemiology, Clinical Signs and Diagnostics

Animals, 2023
The breeding of South American Camelids (SACs), particularly llamas and alpacas, is becoming increasingly popular in regions that are not their natural habitat, including Europe. These animals are considered to be relatively disease resistant.
Kacper Konieczny, Małgorzata Pomorska-Mól   +1 more
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source