Results 91 to 100 of about 30,535,003 (216)
ABSTRACT In persistent HPS‐related hypoxemia after LT, prolonged VV‐ECMO can serve as a bridge to recovery when conventional oxygenation strategies fail. Serial contrast‐enhanced echocardiography and multidisciplinary management may support weaning decisions and the management of ECMO‐related complications.
Paweł Topolewski +9 more
wiley +1 more source
Migraine Causality in Alpha-1 Antitrypsin Deficiency
Alpha1-antitrypsin (A1AT) is an anti-inflammatory mediator with antiprotease activity associated with anti-inflammatory and immunomodulatory effects in various inflammatory conditions.
Esra Demir Unal
doaj +1 more source
ABSTRACT Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and remains a major cause of cancer‐related mortality worldwide. Its poor clinical outcomes are largely attributed to late‐stage diagnosis and the limited accuracy of currently available diagnostic and prognostic biomarkers.
Jana Hamad +2 more
wiley +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Alpha-1 antitrypsin deficiency-associated panniculitis: a case report
Alpha-1 antitrypsin deficiency is a hereditary disorder with predominantly pulmonary but also extrapulmonary manifestations. In the skin, it is associated with panniculitis, a necrotizing neutrophilic inflammation in the subcutis. Clinically, it presents
Špela But +2 more
doaj +1 more source
ABSTRACT Background and Aims Major Depressive Disorder (MDD) is a highly common neuropsychiatric disorder globally. A variety of factors contribute to the neuropathology of MDD. Microbiome research in neuropsychiatric disorders such as MDD has recently attracted attention. Indeed, the gut‐brain axis could influence the course of MDD through metabolites
Nazanin Zahra Keshvari +6 more
wiley +1 more source
Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley +1 more source
High BMI and COPD Outcomes in Alpha-1 Antitrypsin DeficiencyTake-Home Points
Background: Elevations in BMI impact morbidity in patients with COPD in general, but little is known about its impact in patients with COPD due to alpha-1 antitrypsin deficiency (AATD-COPD).
Michael A. Campos, MD +4 more
doaj +1 more source
This study evaluated 11 extracellular vesicle (EV) isolation methods which generate plasma‐derived EV‐containing preparations with varying degrees of contaminants. No single approach optimized purity and proteome coverage. In this paper we use proteomics to present an Evidence‐Based Framework to select plasma EV isolation methods based on downstream ...
Scheila Julia Werle +5 more
wiley +1 more source
Felix JF Herth,1 Robert A Sandhaus,2 Alice M Turner,3 Maria Sucena,4 Tobias Welte,5 Timm Greulich6 1Department of Pneumology and Critical Care Medicine, University of Heidelberg, Heidelberg, Germany; 2Division of Pulmonary, Critical Care and Sleep ...
Herth FJF +5 more
doaj

