Results 131 to 140 of about 107,093 (255)

Treatment of lung disease in alpha-1 antitrypsin deficiency: a systematic review

, 2017
Ross G Edgar,1,2 Mitesh Patel,3 Susan Bayliss,4 Diana Crossley,2,5 Elizabeth Sapey,2,5 Alice M Turner4,6 1Therapy Services, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; 2Institute of Inflammation and Ageing, University of ...
Edgar RG, Crossley D, Bayliss S, Patel M, Sapey E, Turner AM   +5 more
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Alpha-1 proteinase inhibitors for the treatment of alpha-1 antitrypsin deficiency: safety, tolerability, and patient outcomes

, 2015
Sanjay H Chotirmall,1 Mazen Al-Alawi,2 Thomas McEnery,2 Noel G McElvaney2 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 2Department of Respiratory Medicine, Beaumont Hospital, Dublin, Republic of Ireland Abstract ...
Chotirmall SH, McEnery T, McElvaney NG, Al-Alawi M   +3 more
core  

Alpha-1 Antitrypsin Deficiency Screening Using Serum Protein Electrophoresis [PDF]

Background: Alpha-1 antitrypsin is encoded by the polymorphic SERPINA1 gene, with pathogenic variants causing alpha-1 antitrypsin deficiency.
García-Zafra, Laura, García-Gutiérrez, Almudena, del Castillo-Díez, Enrique, Perales-Afán, Juan José, Torralba-Cabeza, Miguel Ángel, Menao, Sebastián   +5 more
core   +1 more source

Alpha-1 antitrypsin deficiency-associated panniculitis: a case report

Zdravniški Vestnik
Alpha-1 antitrypsin deficiency is a hereditary disorder with predominantly pulmonary but also extrapulmonary manifestations. In the skin, it is associated with panniculitis, a necrotizing neutrophilic inflammation in the subcutis. Clinically, it presents
Špela But, Maja Jerše, Pij Bogomir Marko   +2 more
doaj   +1 more source

Alpha-1 antitrypsin deficiency in a French General Hospital: fortuitous detection rather than efficient screening

, 2018
Introduction: We studied the characteristics of the screening procedure for alpha-1 antitrypsin at Nevers Hospital (France), together with the performance of serum protein gel electrophoresis for the fortuitous detection of patients with deficiency ...
Kherouf, Hakim; Centre Hospitalier de l'Agglomération de Nevers - Laboratoire de biologie médicale, 1, boulevard de l'Hôpital, 58000 Nevers, France, Bourgerette, Evelyne; Centre Hospitalier de l'Agglomération de Nevers - Laboratoire de biologie médicale, 1, boulevard de l'Hôpital, 58000 Nevers, France, N'Guyen, Tu; Centre Hospitalier de l'Agglomération de Nevers - Département de l'Information médicale, 1, boulevard de l'Hôpital, 58000 Nevers, France, de Faverges, Geoffroy; Centre Hospitalier de l'Agglomération de Nevers - Service de Pneumologie, 1, boulevard de l'Hôpital, 58000 Nevers, France, Moquet, Olivier; Centre Hospitalier de l'Agglomération de Nevers - Laboratoire de biologie médicale, 1, boulevard de l'Hôpital, 58000 Nevers, France, Dumont, Pierre; Centre Hospitalier de l'Agglomération de Nevers - Laboratoire de biologie médicale, 1, boulevard de l'Hôpital, 58000 Nevers, France   +5 more
core   +2 more sources

High BMI and COPD Outcomes in Alpha-1 Antitrypsin DeficiencyTake-Home Points

CHEST Pulmonary
Background: Elevations in BMI impact morbidity in patients with COPD in general, but little is known about its impact in patients with COPD due to alpha-1 antitrypsin deficiency (AATD-COPD).
Michael A. Campos, MD, Leonard Riley, MD, Jorge Lascano, MD, Brian Garnet, MD, Robert Sandhaus, MD, PhD   +4 more
doaj   +1 more source

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency

, 2009
Irina Petrache1, Joud Hajjar1, Michael Campos21Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Miller School of Medicine ...
Campos, Michael, Michael Campos, Irina Petrache, Joud Hajjar, Hajjar, Joud, Petrache, Irina   +5 more
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Alpha 1 Antitrypsin Therapy in Patients with Alpha 1 Antitrypsin Deficiency: Perspectives from a Registry Study and Practical Considerations for Self-Administration During the COVID-19 Pandemic

International Journal of COPD, 2021
Felix JF Herth,1 Robert A Sandhaus,2 Alice M Turner,3 Maria Sucena,4 Tobias Welte,5 Timm Greulich6 1Department of Pneumology and Critical Care Medicine, University of Heidelberg, Heidelberg, Germany; 2Division of Pulmonary, Critical Care and Sleep ...
Herth FJF, Sandhaus RA, Turner AM, Sucena M, Welte T, Greulich T   +5 more
doaj  

Improving adherence to alpha-1 antitrypsin deficiency screening guidelines using the pulmonary function laboratory

, 2017
Landy V Luna Diaz,1 Isabella Iupe,1 Bruno Zavala,1 Kira C Balestrini,1 Andrea Guerrero,1 Gregory Holt,1,2 Rafael Calderon-Candelario,1,2 Mehdi Mirsaeidi,1,2 Michael Campos1,21Miami Veterans Administration Medical Center, Miami, FL, 2Division of Pulmonary,
Luna Diaz LV, Calderon-Candelario R, Zavala B, Guerrero A, Balestrini KC, Campos M, Iupe I, Mirsaeidi M, Holt G   +8 more
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Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency

, 2017
This review seeks to give an overview of alpha-1 antitrypsin deficiency, including the different disease phenotypes that it encompasses. We then describe the different therapeutic endeavors that have been undertaken to address these different phenotypes.
Flotte, Terence R., Gruntman, Alisha M
core   +1 more source