Results 151 to 160 of about 410,523 (291)
Alpha-1 Antitrypsin Attenuates M1 Microglia-Mediated Neuroinflammation in Retinal Degeneration
Neurodegenerative diseases are a set of disorders characterized by progressive neuronal death and are associated with microglia-mediated neuroinflammation.
Tian Zhou +9 more
semanticscholar +1 more source
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang +5 more
wiley +1 more source
Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 1: Executive summary [PDF]
The feasibility of the commercial manufacturing of pharmaceuticals in space is examined. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process ...
core +1 more source
Alpha-1 Antitrypsin Deficiency Associated Panniculitis.
A. Franciosi +7 more
semanticscholar +1 more source
A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava +4 more
wiley +1 more source
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley +1 more source
Cirrhosis of Liver in Patients With Dyskeratosis Congenita: A Report of Two Cases
Classical mucocuaneous triad of dyskeratosis congenita in a patient with decompensated cirrhosis. ABSTRACT Dyskeratosis congenita (DC) is a genetic disorder characterized by multisystem involvement. The most commonly affected systems are the mucocutaneous, bone marrow, and lungs.
Bigyan Maharjan +8 more
wiley +1 more source
Serum Alpha 1 Antitrypsin and Pulmonary Emphysema [PDF]
Using isoelectric focusing (lEE) and radial immunodiffusion (RID) techniques, serum samples from 100 normal healthy adults and 21 patients with pulmonary emphysema were analysed to identify varioud alpha 1 antitrypsin phenotypes and the Seru m ...
Ansari, Musawir +5 more
core +1 more source
Genetic variants underlying precancerous conditions of hepatocellular carcinoma
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero +7 more
wiley +1 more source
Lafora Disease Masquerading as Hepatic Dysfunction [PDF]
Lafora disease is fatal intractable progressive myoclonic epilepsy. It is frequently characterized by epileptic seizures, difficulty walking, muscle spasms, and dementia in late childhood or adolescence.
Abdullah, Hafez Mohammad A. +6 more
core +1 more source

