Results 191 to 200 of about 42,616 (247)

Human Alpha-1 Antitrypsin Suppresses Melanoma Growth by Promoting Tumor Differentiation and CD8⁺ T-Cell-Mediated Immunity. [PDF]

Biomolecules
Yamauchi T, Luo Y, Menon DR, Couts K, Khan S, Goel A, Dinarello CA, Zhai Z, Fujita M.   +8 more
europepmc   +1 more source

Prevalence of genetic mutations in Alpha-1 antitrypsin in patients with difficult-to-treat asthma in Colombia. [PDF]

BMC Pulm Med
Alí-Munive A, Chacón JL, Prada L, Proaños NJ, Vargas L, Diaz-Bossa C, Giraldo A, Pedrozo-Pupo J.   +7 more
europepmc   +1 more source

Liver transplantation and portacaval shunt in genetic diseases [PDF]

, 1982
Starzl, TE
core  

Applications of Artificial Intelligence in Alpha-1 Antitrypsin Deficiency: A Systematic Review from a Respiratory Medicine Perspective. [PDF]

Medicina (Kaunas)
Casal-Guisande M, Villar-Aguilar L, Fernández-Villar A, García-Rodríguez E, Casal A, Torres-Durán M.   +5 more
europepmc   +1 more source

Alpha-1 antitrypsin deficiency with the rare IZ phenotype presenting as cystic lung disease. [PDF]

BMJ Case Rep
Reed TJ, Shisler R, Collins J.
europepmc   +1 more source

Alpha-1 antitrypsin deficiency [PDF]

Respiratory Medicine, 2010
To review the topic of alpha-1 antitrypsin (AAT) deficiency.Narrative literature review.Much work has been carried out on this condition with many questions being answered but still further questions remain.AAT deficiency is an autosomal co-dominantly inherited disease which affects the lungs and liver predominantly.
Catherine M Greene, Tomás P Carroll
exaly   +6 more sources

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Alpha‐1‐Antitrypsin Deficiency

Clinical Liver Disease, 2022
Content available: Author Audio Recording.
Anandini Suri, Dhiren Patel, Jeffery Teckman   +2 more
openaire   +2 more sources

Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency

The American Journal of Medicine, 1988
Alpha-1-antitrypsin (A1AT) deficiency is a genetic disorder characterized by low serum levels of A1AT and a high risk for the development of emphysema. A1AT is the principal inhibitor of neutrophil elastase, such that a deficiency of A1AT results in insufficient anti-elastase protection in the lower respiratory tract, thus allowing neutrophil elastase ...
R C, Hubbard, R G, Crystal
openaire   +2 more sources

Alpha-1 Antitrypsin Deficiency

2023
Alpha-1 antitrypsin (AAT) deficiency is a common monogenic disorder in which there is a strong founder effect of a single missense mutation in SERPINA1, the gene encoding this major circulating serum anti-protease that is normally expressed primarily in hepatocytes.
Alisha M, Gruntman, Wen, Xue, Terence R, Flotte   +2 more
openaire   +2 more sources

Alpha-1-antitrypsin in malakoplakia

Virchows Archiv A Pathological Anatomy and Histology, 1982
Macrophages in malakoplakia contain large amounts of immunoreactive alpha-1-antitrypsin (AAT). The amount of AAT remains unchanged during the morphogenetic stages of the pathological process (early, granulomatous, fibrosing phases), and does not correlate with the number or the presence of Michaelis-Gutmann (M.G.) bodies.
F, Callea, B, Van Damme, V J, Desmet
openaire   +2 more sources