Results 231 to 240 of about 480,558 (290)

Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis. [PDF]

Inflammation
Li X, Liu L, Tong S, Wang F, Zhu L, Cheng Q, Zhang P, Chen M, Xie Y, Wang L, Yu H, Wu H.   +11 more
europepmc   +1 more source

Orthotopic liver transplantation [PDF]

, 1995
Gordon, RD, Starzl, TE, Van Thiel, DH
core  

Correction to 'Underdiagnosis of Alpha-1 Antitrypsin Deficiency in Cirrhotic Liver Transplant Candidates: Findings From a Multicenter Retrospective Study'. [PDF]

Aliment Pharmacol Ther
europepmc   +1 more source

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Alpha-1 antitrypsin deficiency: a re-surfacing adult liver disorder.

Journal of Hepatology, 2021
Alpha-1 antitrypsin deficiency (AATD) arises from mutations in the SERPINA1 gene encoding alpha-1 antitrypsin (AAT) that lead to AAT retention in the endoplasmic reticulum of hepatocytes, causing proteotoxic liver injury and loss-of-function lung disease.
M. Fromme, C. Schneider, C. Trautwein, N. Brunetti‐Pierri, P. Strnad   +4 more
semanticscholar   +1 more source

Alpha‐1‐Antitrypsin Deficiency

Clinical Liver Disease, 2022
Content available: Author Audio Recording.
Anandini Suri, Dhiren Patel, Jeffery Teckman   +2 more
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Alpha-1 Antitrypsin Deficiency

2023
Alpha-1 antitrypsin (AAT) deficiency is a common monogenic disorder in which there is a strong founder effect of a single missense mutation in SERPINA1, the gene encoding this major circulating serum anti-protease that is normally expressed primarily in hepatocytes.
Alisha M, Gruntman, Wen, Xue, Terence R, Flotte   +2 more
openaire   +2 more sources

Alpha-1 Antitrypsin Deficiency Associated COPD.

Clinics in Chest Medicine, 2020
Alpha-1 antitrypsin deficiency (AATD) was the first genetic risk factor for chronic obstructive pulmonary disease (COPD) described. In the more than 50 years since its description, the disease continues to provide insights into more common forms of COPD.
C. Strange
semanticscholar   +1 more source

Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency

The American Journal of Medicine, 1988
Alpha-1-antitrypsin (A1AT) deficiency is a genetic disorder characterized by low serum levels of A1AT and a high risk for the development of emphysema. A1AT is the principal inhibitor of neutrophil elastase, such that a deficiency of A1AT results in insufficient anti-elastase protection in the lower respiratory tract, thus allowing neutrophil elastase ...
R C, Hubbard, R G, Crystal
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Clinical and histologic features of adults with alpha-1 antitrypsin deficiency in a non-cirrhotic cohort.

Journal of Hepatology, 2018
BACKGROUND & AIMS Alpha-1 antitrypsin deficiency (AATD) is an uncommonly recognized cause of liver disease in adults, with descriptions of its natural history limited to case series and patient-reported data from disease registries.
V. Clark, George Marek, Chen Liu, Amy Collinsworth, Jonathan Shuster, T. Kurtz, Joanna L Nolte, M. Brantly   +7 more
semanticscholar   +1 more source

Alpha-1 Antitrypsin Deficiency

Journal of Insurance Medicine, 2015
Alpha-1 antitrypsin deficiency is an inherited disorder that may cause severe lung and liver disease.
openaire   +2 more sources