Results 61 to 70 of about 26,843 (195)

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley   +1 more source

Exacerbations, health status and sibling pair comparisons in severe Alpha-1-Antitrypsin Deficiency

, 2007
Alpha-1-Antitrypsin Deficiency (AATD) is a risk factor for the development of early-onset emphysema and airflow obstruction. The current work defines exacerbations, lung function and health status in these patients including sibling pairs.
Needham, Michelle
core  

Alpha-1-antitrypsin deficiency

, 2021
The subject of this review is alpha-1-antitrypsin deficiency (A1AD), which is a rare hereditary disease with great impact in adults, especially smokers, quality of life and longevity. Early diagnosis is crucial for treatment outcome.
Jensen, Jens-Ulrik, de Vos, Jesper Dichmann, Wilcke, Jon Torgny, Løkke, Anders, Hillberg, Ole, Perch, Michael   +5 more
core  

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared, Fatemeh Shahabi, Asieh Sadat Fattahi, Marzieh Rahimi, Mahsa Akbari Oryani, Azadeh Jabbari Nooghabi   +5 more
wiley   +1 more source

An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein.

, 2015
A monoclonal antibody (mAb) that binds to a transient intermediate may act as a catalyst for the corresponding reaction; here we show this principle can extend on a macro-molecular scale to the induction of mutant-like oligomerisation in a wild-type ...
Faull, SV, Lomas, DA, Perez, J, Irving, JA, Kotov, VR, Haq, I, Miranda, E, Motamedi-Shad, N   +7 more
core  

Programmed Cell Death in Chronic Rhinosinusitis

Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu, Junying Hu, Weigang Gan, Qi Wu, Bing Zhong, Feng Liu   +5 more
wiley   +1 more source

Clinical significance of urinary SPP1 as a potential new diagnostic marker for oesophageal squamous cell carcinoma

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
In this study, we investigate the potential of urinary secreted phosphoprotein 1 (SPP1) levels as a noninvasive diagnostic biomarker for oesophageal squamous cell carcinoma (ESCC). Our study suggests that urinary SPP1 may serve as a novel biomarker for the detection of ESCC. Abstract Background Urinary proteins could be useful as noninvasive biomarkers
Bingrong Guo, Jiawei Zhang, Jianpeng Che, Yuan Zhong, Linlin Ji, Wei Li   +5 more
wiley   +1 more source

Mosunetuzumab Successfully Treated Rituximab‐Refractory Lymphoma‐Associated Protein‐Losing Enteropathy With Concomitant Immune Thrombocytopenia in Follicular Lymphoma: A Case Report

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Protein‐losing enteropathy (PLE) is a rare but potentially severe complication of malignant lymphoma characterized by excessive gastrointestinal loss of plasma proteins, leading to hypoalbuminemia, edema, and serous effusions. We report a case of follicular lymphoma complicated by severe PLE and concomitant immune thrombocytopenia (ITP ...
Takashi Matsunaga, Naohi Sahara, Mai Mizusawa, Yukiko Miura, Seiichiro Kobayashi, Tomoki Fujii, Nobuhiro Oono   +6 more
wiley   +1 more source

The Plasma Free Fatty Acid Carrier Proteome is Altered in Diet‐Induced and Genetically Obese Mice

Obesity, Volume 34, Issue 6, Page 1300-1313, June 2026.
ABSTRACT Objective We aimed to examine the effect of obesity on the plasma free fatty acid (FFA) carrier proteome in mice. Methods From 6 to 20 weeks of age, male and female C57BL/6J wild‐type mice were fed either a low‐fat diet (10% of kilocalories from fat) or a high‐fat diet (60% of kilocalories from fat), and leptin‐deficient ob/ob mice were fed a ...
Keigo Tomoo, Yi Zhang, Ariana Zoe Diaz Portalatin, Gregory C. Henderson   +3 more
wiley   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source