Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen +6 more
wiley +1 more source
Mass decomposition dynamics and soil microbial community changes during the photodegradation process of leaf litter from three plant species in hyper-arid deserts. [PDF]
Fan L, Lin L, Li X.
europepmc +1 more source
Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner +8 more
wiley +1 more source
There is an "I" in team: individual improvements in supercharged cellulase cocktail facilitates cooperative cellulose degradation. [PDF]
DeChellis A +5 more
europepmc +1 more source
On the relationship between chemical composition and digestibility in vivo of roughage [PDF]
Dijkhuis, J.G., Heida, S., Muller, F.M.
core +1 more source
Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos +6 more
wiley +1 more source
A multi-enzyme producing <i>Bacillus subtilis</i> YCXW-01: Isolation, genomic characterization, and potentials in tobacco stem degradation. [PDF]
Yang Z +6 more
europepmc +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Pulmonary inflammation and immune responses induced by nanocellulose: Insights from <i>in vivo</i> and <i>in vitro</i> models. [PDF]
Fujita K +5 more
europepmc +1 more source

