Results 31 to 40 of about 884,292 (292)

Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe3O4 magnetic nanoparticles

open access: yes, 2014
For preoperative and intraoperative detection of tumor distribution, numerous multi-modal contrast agents, such as magnetic nanoparticles (MNPs) with several examination indicators, are currently in development. However, complex materials, configuration,
Huang, Kai-Wen;Chieh, Jen-Jie;Horng, Herng-Er;Hong, Chin-Yih;Yang, Hong-Chang   +1 more
core   +1 more source

ALPHA FETOPROTEIN; A PROGNOSTIC MARKER FOR EARLY DETECTION OF LIVER REGENERATION IN CASES OF ACUTE PARACETAMOL TOXICITY [PDF]

open access: yesThe Egyptian Journal of Forensic Sciences and Applied Toxicology, 2018
Background: Acute paracetamol toxicity is one of the commonest toxicities that lead to serious hepatic injury that could propagate to fulminant hepatic failure. An increase in serum level of alpha fetoprotein was observed following liver injury, and this
doaj   +1 more source

Alpha-Fetoprotein: A Review

open access: yesJournal of Investigative Dermatology, 1979
Detection and measurement of serum AFP levels have been found useful in the diagnosis, prognosis and follow up of patients with hepatoma and germ cell tumors [20]. Monitoring maternal and amniotic fluid AFP concentration helps detect a variety of fetal disorders. The in vitro evidence for immunosuppressive effects of AFP suggests a possible role of AFP
openaire   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Serum PIVKA-II and alpha-fetoprotein at virological remission predicts hepatocellular carcinoma in chronic hepatitis B related cirrhosis

open access: yesJournal of the Formosan Medical Association, 2022
Background: The risk of hepatocellular carcinoma (HCC) is reduced but not eliminated after nucleos(t)ide analogue (NA) therapy in chronic hepatitis B (CHB).
Tung-Hung Su   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

15-Year-Old Patient with an Unusual Alpha-Fetoprotein-Producing Sertoli-Leydig Cell Tumor of Ovary

open access: yesCase Reports in Obstetrics and Gynecology, 2022
Ovarian Sertoli-Leydig cell tumors (SLCTs) are extremely rare ovarian sex-cord stromal tumors. Alpha-fetoprotein (AFP) production by SLCTs is a rare event generally linked to the presence of hepatocytes or intestinal mucinous epithelium as heterologous ...
Kaçar Serife   +4 more
doaj   +1 more source

Characterizations of Anti-Alpha-Fetoprotein-Conjugated Magnetic Nanoparticles Associated with Alpha-Fetoprotein for Biomedical Applications

open access: yesSensors, 2017
In this work, we report characterizations of biofunctionalized magnetic nanoparticles (BMNPs) associated with alpha-fetoprotein (AFP) for biomedical applications. The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-
Shu-Hsien Liao   +5 more
doaj   +1 more source

Early Alpha-Fetoprotein Response Predicts Treatment Efficacy of Antiangiogenic Systemic Therapy in Patients with Advanced Hepatocellular Carcinoma

open access: yes, 2011
BACKGROUND: Antiangiogenic therapy has become the most important treatment modality for patients with advanced hepatocellular carcinoma ( HCC). In this study, the authors investigated levels of alpha-fetoprotein (AFP) as a potential biomarker for ...
SHAO, YU-YUN;LIN, ZONG-ZHE;HSU, CHIUN;SHEN, YING-CHUN;HSU, CHIH-HUNG;CHENG, ANN-LII   +1 more
core   +1 more source

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