Results 71 to 80 of about 884,292 (292)
FlexMat, EarlyView.Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue +5 more
wiley +1 more source
Presence of serum alpha-1-fetoprotein in alcoholic hepatitis
, 1975 Alpha-Fetoprotein was detected in a patient with alcoholic hepatitis during the acute phase of the illness. The alpha-fetoprotein was no longer detected as clinical improvement developed.
Moral, M D, Schiff, E R, Miller, A I
core +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
FlexMat, EarlyView.This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Extreme Elevation of Serum Alpha Fetoprotein in Decompensated Cirrhosis without Hcc: an Ominous Sign
The International Journal of Biological Markers, 2007 Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation.
H. Senturk MD, R. Cumali
doaj +1 more source
Health Care Science, EarlyView.The T cell‐inflamed gene expression profile (GEP) provides a biomarker for immunotherapy response across various cancers. We established a CT‐based radiomics model to predict the T cell‐inflamed GEP and immunotherapy response in hepatocellular carcinoma (HCC).
Mimi Tang +11 more
wiley +1 more source
Prognostic roles of pathology markers immunoexpression and clinical parameters in Hepatoblastoma
Journal of Biomedical Science, 2017 Background Hepatoblastoma, a leading primary hepatic malignant tumor in children, is originated from primitive hepatic stem cells. We aimed to elucidate the relationships between the histological distribution of β-catenin and hepatic stem cell markers ...
Jia-Feng Wu +6 more
doaj +1 more source
Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
Canadian Journal of Gastroenterology and Hepatology, 2018 Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha-fetoprotein (AFP) possesses a variety of biological functions. Except
Xiaoping Wang, Qiaoxia Wang
doaj +1 more source
Hereditary persistence of alpha-fetoprotein
Chinese Journal of Cancer Research, 1994 A proband with persistently elevated AFP levels ranging between 21-129 ng/ml with median of 90 ng/ml has been found and observed for 1 year. Family studies have revealed that his father had had persistent AFP elevation for 4 years, ranging from 46 to 198.2 ng/ml, with median level of 93 ng/ml. His brother also has elevated AFP level.
Y Z, Feng, J, Liu, X R, Zhou
openaire +2 more sources
Structure of the alpha-fetoprotein gene in the mouse. [PDF]
, 1980 The mouse alpha-fetoprotein mRNA is the product of a single-copy gene whose mRNA coding sequences are represented discontinuously in the genome. Several EcoRI genomic fragments which contain portions of the alpha-fetoprotein gene have been cloned using ...
Gorin, M B +3 more
core +1 more source
Various Hepatic Fibrosis Markers Should Be Evaluated for Causing Complications After Hepatectomy
Annals of Gastroenterological Surgery, EarlyView.
Toru Ikegami +3 more
wiley +1 more source