Results 111 to 120 of about 835,413 (266)
Andrology, EarlyView.Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann +9 more
wiley +1 more source
A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer
Andrology, EarlyView.ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner +7 more
wiley +1 more source
Alpha Sigma Alpha Scrapbook, 1984-1985 [PDF]
, 1985 https://digitalcommons.longwood.edu/alpha-sigma-alpha_scrapbooks/1006/thumbnail ...
Longwood University, Alpha Sigma Alpha
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Andrology, EarlyView.ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup +7 more
wiley +1 more source
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Neoplastic Risk in Patients With Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani +4 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova +6 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Sex chromosome aneuploidies represent a heterogeneous group of chromosomal conditions, in which phenotypic complexity generally increases with the number of supernumerary sex chromosomes. While Turner syndrome and sex chromosome trisomies are relatively well characterized, less is known about congenital malformations in sex chromosome ...
Anna Colding +3 more
wiley +1 more source
Impact of Single Viable Hepatocellular Carcinoma ≤ 3 cm on Survival After Liver Transplantation
ANZ Journal of Surgery, EarlyView.An Australian multi‐centre cohort study shows significantly lower 5‐year HCC‐specific mortality for those with no viable disease compared to those with a single viable tumour ≤ 3 cm, on imaging prior to transplantation. A lower AFP level and complete response on mRECIST criteria also reduced risk.
Lauren C. Y. Tang +12 more
wiley +1 more source