NAFLD‐related hepatocellular carcinoma: The growing challenge
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
Materials and methods: A retrospective analysis of all paediatric patients diagnosed and treated for gastric teratomas in our hospital over the past 20 years was carried out (1997–2017).
Namita Bhutani, Pradeep Kajal
doaj +1 more source
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai +29 more
wiley +1 more source
Intracranial yolk sac tumor in an adult patient: MRI, diffusion-weighted imaging and 1H MR spectroscopy features [PDF]
Introduction. Yolk sac tumors represent only 5%-7% of intracranial germ cell tumors, which comprise about 1% of all primary brain tumors in adults. Literature data about nonspecific imaging characteristics of these tumors are scant.
Mačvanski Marija +7 more
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The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
The Association between Second-Trimester Maternal Serum Alpha-Fetoprotein in 14-22 Weeks and Adverse Pregnancy Outcome [PDF]
Aim of this study is to determine the risk of adverse pregnancy outcome by maternal serum alphafetoprotein (MSAFP) level. We followed 295 pregnant women from MSAFP screening in the 14th to 22th week of gestation until the end of pregnancy and information
Razieh Dehghani–Firouzabadi +3 more
doaj +1 more source
Hepatoid adenocarcinoma of stomach: Case report of a rare histological variant
Hepatoid adenocarcinoma of the stomach is a rare form of gastric carcinoma with specific clinicopathological features and extremely poor prognosis. Here, we report a case of a 60-year-old male patient who presented in the outpatient department with pain ...
Vidisha Mahajan +3 more
doaj +1 more source
Isolated eyeball metastasis of non-seminomatous germ cell testicular tumor [PDF]
Introduction. Testicular tumors most frequently metastasize to regional lymph nodes. Non-seminomatous tumor metastasis of testicle (NSGCTT) to the eyeball is rare. Case report.
Bojanić Nebojša +5 more
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Proteomic Analysis of Fetal Ovary Reveals That Ovarian Developmental Potential Is Greater in Meishan Pigs than in Yorkshire Pigs. [PDF]
Time-dependent expression of functional proteins in fetal ovaries is important to understand the developmental process of the ovary. This study was carried out to enhance our understanding of the developmental process of porcine fetal ovaries and to ...
Mengmeng Xu +11 more
doaj +1 more source
Pregnancy outcomes of women with elevated second-trimester maternal serum alpha-fetoprotein
Objective: The aim of this study was to investigate the overall distribution of pregnancy outcomes in women with elevated second-trimester maternal serum alpha-fetoprotein (MS-AFP), and to determine the risk of adverse pregnancy outcomes (APOs) by MS-AFP
Ji-Lin Hu +10 more
doaj +1 more source

