Results 141 to 150 of about 4,902,736 (350)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The History of Milk Pasteurization in Iran and the Role of Pasteur Institute in Its improvement
Journal of Medical Microbiology and Infectious Diseases, 2018 In November 1950, a relatively modern factory, called Alpha, was established in Javadiyeh district of Tehran. It was the first factory of milk pasteurization in Iran, which started by pasteurizing five tons of milk per day and manufacturing dairy ...
Sholeh Maslehat, Ehsan Mostafavi
doaj
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Isotype diversity of antibodies to alpha-gal Including IgG3 as well as IgE and the possible relevance to coronary artery disease [PDF]
Lisa J. Workman +6 more
openalex +1 more source
Alpha-IoU: A Family of Power Intersection over Union Losses for Bounding Box Regression [PDF]
, 2021 Jiabo He +5 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Diagnostic role of p16/INK4A protein in Human Papillomavirus (HPV) induced cervical dysplasia
Open Life Sciences, 2010 Rajčáni Július +4 more
doaj +1 more source