Results 201 to 210 of about 4,902,736 (350)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues

, 2015
Charles Zhu, Amey Bandekar, Michelle Sempkowski, Sangeeta Ray Banerjee, Martin G. Pomper, Frank Bruchertseifer, Aliyah Morgenstern, Stavroula Sofou   +7 more
openalex   +1 more source

The leftward deletion alpha-thal-2 haplotype in a black subject with hemoglobin SS [PDF]

, 1985
SH Embury, MA Gholson, Peter Gillette, RF Rieder   +3 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

DMT-Induced Shifts in Criticality Correlate with Self-Dissolution. [PDF]

J Neurosci
Irrmischer M, Aqil M, Luan L, Wang T, Engelbregt H, Carhart-Harris R, Linkenkaer-Hansen K, Timmermann C.   +7 more
europepmc   +1 more source

greydongilmore/trajectoryGuideModules: v1.2.6-alpha

Greydon Gilmore
openalex   +1 more source

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes

, 2018
Shanhang Jia, Mark T. Miedel, Marilyn Ngo, Ryan Hessenius, Ning Chen, Peilu Wang, Amir Bahreini, Zheqi Li, Zhijie Ding, Tong Ying Shun, Daniel M. Zuckerman, D. Lansing Taylor, Shannon L. Puhalla, Adrian V. Lee, Steffi Oesterreich, Andrew M. Stern   +15 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Alpha-band echoes evoked by contrast and luminance changes emerge in and travel out from early visual cortex. [PDF]

J Vis
Morrow A, Turkovich E, Sankaran S, Pilipenko A, Samaha J.   +4 more
europepmc   +1 more source

allen-proxmire/delta-alpha-zeta-zero: Delta-Alpha Zeta Zero; pre-print; very early draft

allen-proxmire
openalex   +1 more source