Results 131 to 140 of about 24,735 (239)

Serum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2019
Nozomu Takei,1,* Masaru Suzuki,1,* Hironi Makita,2 Satoshi Konno,1 Kaoruko Shimizu,1 Hiroki Kimura,1 Hirokazu Kimura,1 Masaharu Nishimura1,2 1Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University ...
Takei N, Suzuki M, Makita H, Konno S, Shimizu K, Kimura H, Kimura H, Nishimura M   +7 more
doaj  

The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity. [PDF]

, 2014
Pathological inflammation and autoimmune disease frequently involve elevated neutrophil activity in the absence of infectious agents. Tumor necrosis factor-α (TNF-α) contributes to many of the problems associated with autoimmune diseases. We investigated
Bergin, David A, Fitzgerald, Sean, Hurley, Killian, Jameel, Ramia, McElvaney, Noel G, Reeves, Emer P, Wolfe, Rebecca   +6 more
core   +1 more source

The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals

Journal of Inflammation Research, 2018
Danielle M Dunlea, Laura T Fee, Thomas McEnery, Noel G McElvaney, Emer P Reeves Irish Centre for Genetic Lung Disease, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland Abstract: Alpha-1 antitrypsin (AAT) is
Dunlea DM, Fee LT, McEnery T, McElvaney NG, Reeves EP   +4 more
doaj  

Alpha 1-antitrypsin deficiency and related liver disease

The Saudi Journal of Gastroenterology, 1999
α1 ,-antitrypsin (α1 AT) deficiency is a relatively common genetic cause of liver disease among Caucasians. It is an autosomal recessive disorder characterized by reduced serum levels of α1 AT, a 52-kD glycoprotein that functions as an ...
Elzouki Abdul-Nasser
doaj  

The Epidemiology of Alpha-1 Antitrypsin Deficiency in Norway. [PDF]

Clin Epidemiol
Ghanima W, Vágó EK, Acquavella J, Horváth-Puhó E.   +3 more
europepmc   +1 more source

RNA editing for the treatment of alpha-1 antitrypsin deficiency. [PDF]

Nucleic Acids Res
Monian P, Shivalila C, Lu G, Bowman K, Briem S, Bylsma M, Byrne M, Cannon M, Chatterjee A, Dallaire M, Desai J, Dufresne J, Faraone A, Favaloro F, Friend S, Ghosh A, Godfrey J, Hernandez N, Huth O, Iwamoto N, Kawamoto T, Lamattina A, Lemaitre M, Lindsey A, Liu F, Looby R, Luu K, McGlynn A, Metterville J, Paik IH, Pan Q, Patil S, Pu T, Purcell-Estabrook E, Ranade A, Rheinhardt J, Rossi J, Shimizu M, Singh K, Standley S, Thomas C, Tripathi S, Yang H, Yordanoff R, Yin Y, Yu H, Narayanan P, Kandasamy P, Giangrande PH, Vargeese C.   +49 more
europepmc   +1 more source

Quantitative analysis of chest computed tomography in alpha-1-antitrypsin deficiency. [PDF]

Respir Res
Höger P, Benholz J, Weinheimer O, Wielpütz MO, Heußel CP, Bischoff A, Eberhardt R, Buschulte K, Fähndrich S, Michels-Zetsche JD, Ersöz H, Rivera AO, Herth F, Trudzinski FC.   +13 more
europepmc   +1 more source

Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA. [PDF]

Ther Adv Respir Dis
Höger P, Ries M, Olivares Rivera A, Ersöz H, Buschulte K, Fähndrich S, Kontogianni K, Herth F, Trudzinski FC.   +8 more
europepmc   +1 more source

Alpha-1 antitrypsin deficiency in bronchiectasis: Evidence for an overlooked entity beyond COPD: A retrospective observational study. [PDF]

Medicine (Baltimore)
Özdemir L, Pazarli AC, Gegin S, Özdemir B, Aksu EA, Çubukçu M.   +5 more
europepmc   +1 more source

Alpha-1 antitrypsin deficiency and granulomatosis with polyangiitis: a systematic review and meta-analysis. [PDF]

Eur Respir Rev
Alluhibi R, Baradwaaj S, Heyer-Chauhan N, Marshall A, Lomas DA, Salama AD, Hurst JR.   +6 more
europepmc   +1 more source