Results 141 to 150 of about 169,723 (293)

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

Advanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu, Lu Diao, Jin Wang, Ao Zhu, Xianlan Chen, Yan Zheng, Yuhan Liu, Kang Hu, Jiashan Zhu, Cheng Ding, Chang Li, Yunzhi Pan, Jun Zhao, Mi Liu   +13 more
wiley   +1 more source

Intralesional interferon-alpha therapy in advanced malignant melanoma

, 1988
Peter von Wussow, Berthold Block, Frank Hartmann, H. Deicher   +3 more
openalex   +1 more source

Demonstration of two subtypes of human leukocyte interferon (IFN-alpha) by monoclonal antibodies. [PDF]

, 1982
Makoto Imai, Tokuo SANO, Yoshizo Yanase, Kazuyoshi Miyamoto, Shin Yonehara, Hiroyuki Mori, T Honda, S. Fukuda, Tadashi Nakamura, Yozo Miyakawa, M Mayumi   +10 more
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Family of human alpha-interferon-like sequences.

, 1985
Sheldon I. Feinstein, Y Mory, Yuti Chernajovsky, Luc Maroteaux, Uri Nir, Vered Lavie, Michel Revel   +6 more
openalex   +1 more source

Efficacy of gamma and alpha interferon (IFN) in the treatment of hairy cell leukemia (HCL) [PDF]

, 1986
N. Niederle, O. Kloke, Mohammad R. Nowrousian, H.-J. Kruse, C. G. Schmidt   +4 more
openalex   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

IFNA2: The prototypic human alpha interferon. [PDF]

Gene, 2015
Paul F, Pellegrini S, Uzé G.
europepmc   +1 more source

Alpha-interferon responses in cerebrospinal fluid of patients with suspected meningitis.

, 1987
D O Ho-Yen, D Carrington
openalex   +1 more source

Treatment of hairy cell leukemia with recombinant alpha interferon: II. In vivo down-regulation of alpha interferon receptors on tumor cells [PDF]

, 1986
C Billard, F Sigaux, S Castaigne, F Valensi, G Flandrin, L Degos, E Falcoff, M Aguet   +7 more
openalex   +1 more source