Results 181 to 190 of about 1,649,512 (376)

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

IFNA2: The prototypic human alpha interferon. [PDF]

open access: yesGene, 2015
Paul F, Pellegrini S, Uzé G.
europepmc   +1 more source

Effects of recombinant alpha and gamma interferons on the in vitro growth of circulating hematopoietic progenitor cells (CFU-GEMM, CFU-Mk, BFU-E, and CFU-GM) from patients with myelofibrosis with myeloid metaplasia [PDF]

open access: bronze, 1987
Carmelo Carlo‐Stella   +8 more
openalex   +1 more source

Comparison of Immune Restoration in Early versus Late Alpha Interferon Therapy against Hepatitis C Virus

open access: yesJournal of Virology, 2010
Mohamed S. Abdel-Hakeem   +8 more
semanticscholar   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui   +16 more
wiley   +1 more source

Very long‐term follow‐up results of imatinib mesylate therapy in chronic phase chronic myeloid leukemia after failure of interferon alpha therapy

open access: green, 2012
Hagop M. Kantarjian   +7 more
openalex   +2 more sources

The woodchuck interferon alpha system: cloning, family description and biologic activity [PDF]

open access: bronze, 2002
Pedro Berraondo   +9 more
openalex   +1 more source

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