Results 231 to 240 of about 362,526 (330)

Different Biological Activities of Specific Interferon Alpha Subtypes

mSphere, 2019
Kim J. Hasenkrug, Kerry J. Lavender, Mario L. Santiago, Kathrin Sutter, Ulf Dittmer   +4 more
doaj   +1 more source

Very long‐term follow‐up results of imatinib mesylate therapy in chronic phase chronic myeloid leukemia after failure of interferon alpha therapy

, 2012
Hagop M. Kantarjian, Susan O’Brien, Guillermo Garcia‐Manero, Stefan Faderl, Farhad Ravandi, Elias Jabbour, Jianqin Shan, Jörge E. Cortes   +7 more
openalex   +2 more sources

MCUB Inhibits PRKN‐Dependent Mitophagic Degradation of PD‐L1 to Promote Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, the overexpression of MCUB not only reduces mitochondrial calcium influx but also facilitates its binding to PRKN at Arg51, both mechanisms contribute to the impairment of PRKN‐mediated mitophagy. Consequently, the degradation of PD‐L1 is suppressed, leading to its stable expression on the tumor cell surface.
Yuan Huang, Chen Chen, Mingqiang Su, Dongqing Li, Jinge Zhang, Kuangye Long, Wenbin Nie, Shu Wei, Wei Chen, Haiyong Chen, Zhangfeng Zhong, Lina Hou, Wanlong Tan, Fei Li   +13 more
wiley   +1 more source

The impact of JAK2^V617F variant allele frequency in MPN patients following PEGylated interferon alpha discontinuation. [PDF]

Br J Haematol
Brown R, Bennett R, Crean C, Hindley A, McGimpsey J, Cunningham N, Niblock A, McPherson S, Boyd K, Foy A, Graham C, Greenfield G, McMullin MF, Catherwood MA.   +13 more
europepmc   +1 more source

Response to Alpha-Interferon Treatment of the Congenital Dyserythropoietic Anemia type I in Two Sicilian Beta Thalassemia Carriers. [PDF]

Indian J Hematol Blood Transfus, 2017
Agrigento V, Barone R, Sclafani S, Di Maggio R, Sacco M, Maggio A, D'Alcamo E.   +6 more
europepmc   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

Markers of Antiviral Response in SLE Patients After Vaccination Against SARS-CoV-2. [PDF]

Int J Mol Sci
Komorniczak M, Lisowska KA, Bułło-Piontecka B, Dębska-Ślizień A, Wardowska A.   +4 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Evaluating the feasibility of a network meta-analysis comparing treatment options in polycythemia vera. [PDF]

J Comp Eff Res
Walden P, Hummel N, Kopiec A, Maliszewska Z, Naslazi E.   +4 more
europepmc   +1 more source

ORIGINAL PAPER
Combined interferon-alpha-2b and ribavirin therapy in patients with recurring chronic hepatitis C (genotype 1) following liver transplantation in Hungary

, 2005
Gabriella Lengyel, Laśzló Kob́ori, Imre Fehérvári, Balázs Nemes, Dénes Görög, Attila Patonai, Enikő Sárváry, Marina Varga, Krisztina Hagymási, Ferenc Perner, János Fehér, Zsolt Tulassay   +11 more
openalex   +1 more source