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Journal of Clinical Oncology, 2023
PURPOSE Interferon alfa-2b (IFN alpha-2b) exhibits antitumor activity in metastatic melanoma and on this basis has been evaluated as an adjuvant therapy following surgery for deep primary (T4) or regionally metastatic (N1) melanoma.
J. M. Kirkwood +5 more
semanticscholar +1 more source
PURPOSE Interferon alfa-2b (IFN alpha-2b) exhibits antitumor activity in metastatic melanoma and on this basis has been evaluated as an adjuvant therapy following surgery for deep primary (T4) or regionally metastatic (N1) melanoma.
J. M. Kirkwood +5 more
semanticscholar +1 more source
Interferon Alpha 2a and 2b in Ophthalmology: A Review
Journal of Interferon and Cytokine Research, 2019Interferon alpha (IFN-α) is a glycoprotein with antitumor, antiviral, and immunomodulatory activity, used widely in the treatment of viral infections (hepatitis B and C, condylomata acuminata, herpes zoster, etc.), hematological disorders (leukemia ...
Natalia Lewczuk +2 more
semanticscholar +1 more source
Pharmacology & Therapeutics, 1995
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
M A, Horisberger, S, Di Marco
openaire +2 more sources
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
M A, Horisberger, S, Di Marco
openaire +2 more sources