Results 11 to 20 of about 56,029 (267)
Alphabet «chauvin» ou alphabet «nationaliste» ?
Nous sommes en 1930, année du XVIe Congrès du Parti, où Staline intervient au sujet de la question nationale et de la culture nationale. Il parle de deux «déviations» [uklony] qui tendent, selon lui, à entraver la politique du parti dans la question nationale, à savoir le «chauvinisme de grande puissance» [velikoderžavnyj šovinizm] et le «nationalisme ...
openaire +2 more sources
The Latin Alphabet is the Alphabet of future
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Г. Кaрипбaевa +1 more
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Abstract Inspired by nature, chemists have spent the last 50 years systematically designing and synthesizing a vast array of sugar-modified nucleic acids, so-called xenonucleic acids (XNAs), collectively forming what we now describe as the XNA alphabet.
John C Chaput +2 more
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Tests — Alphabetic/Alphabetic-upper/Alphabetic-lower [PDF]
An item can be tested to check whether it is alphabetic (i.e. contains only letters of the alphabet or spaces):
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

