Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke +4 more
wiley +1 more source
Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination. [PDF]
Weber S, Ramirez CM, Doerfler W.
europepmc +1 more source
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka +27 more
wiley +1 more source
Trans-ankle intervention can be an optimal strategy for aggressive wire recanalization in calcified atheroma and dilatation technique in common femoral artery. [PDF]
Nomura T +8 more
europepmc +1 more source
ABSTRACT Aims To explore the therapeutic impact of D3 lymph node dissection for non‐metastatic colon cancers, evaluating the therapeutic value index for each lymph node station according to surgical stages. Methods Consecutive patients with surgical Stage I–III colon and rectosigmoid cancer who underwent curative resection between January 2003 and ...
Akira Ouchi +9 more
wiley +1 more source
Trajectory classification through Freeman's curve encoding and entropic analysis. [PDF]
Peña-Mendieta R +5 more
europepmc +1 more source
Consolidation of multiple binary distillation columns for large heat duty savings
ABSTRACT The enormous scales of chemical and petrochemical plants present significant challenges in separating and purifying numerous mixed streams generated within a facility, as well as in achieving effective energy utilization and process intensification.
Parikshit S. Kadu, Rakesh Agrawal
wiley +1 more source
Perceptual similarity and clustering in braille letter recognition. [PDF]
Özkan ZG, Baciero A, Perea M, Gómez P.
europepmc +1 more source
Computational study of permeability in cardboard coating layers
Abstract We develop a virtual material structure model based on a combination of tessellations and Gaussian random fields for a coating layer of paperboard used for packaging and designed to facilitate printing on the surface. To fit the model to tomographic image data acquired using combined focused ion beam and scanning electron microscopy (FIB‐SEM),
Sandra Barman +6 more
wiley +1 more source
Quantum Shannon Information Theory-Design of Communication, Ciphers, and Sensors. [PDF]
Hirota O.
europepmc +1 more source

