Molnupiravir Inhibits Replication of Multiple Alphacoronavirus suis Strains in Feline Cells [PDF]
PathogensThe cross-species spillover of coronaviruses is considered a serious public health risk. Feline coronavirus (FCoV), canine coronavirus (CCoV), and transmissible gastroenteritis virus (TGEV) are all classified under Alphacoronavirus suis and infect ...
Tomoyoshi Doki +3 more
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First Detection of Alphacoronavirus in Bats from the World’s Largest Wetland, the Pantanal, Brazil [PDF]
PathogensCoronaviruses (CoV) infect a wide variety of hosts, causing epidemics in humans, birds, and mammals over the years. Bats (order Chiroptera) are one of the natural hosts of the Coronaviridae family. They represent 40% of the total number of mammal species
Tayane B. S. Magalhães +24 more
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Genomic Characterization of a Novel Alphacoronavirus Isolated from Bats, Korea, 2020
Viruses, 2021 Coronavirus, an important zoonotic disease, raises concerns of future pandemics. The bat is considered a source of noticeable viruses resulting in human and livestock infections, especially the coronavirus. Therefore, surveillance and genetic analysis of
Hai-Quynh Do +11 more
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Discovery of Novel Alphacoronaviruses in European Rodents and Shrews [PDF]
Viruses, 2016 Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection.
Theocharis Tsoleridis +13 more
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Virome and Microbiome of Florida Bats Illuminate Viral Co-Infections, Dietary Viral Signals, and Gut Microbiome Shifts [PDF]
MicroorganismsFlorida’s bat virome remains poorly characterized despite the state’s high bat species diversity and conservation importance. We characterized viral metagenomes from rectal tissues, anal swabs, and feces of Myotis austroriparius and Tadarida brasiliensis
Julia E. Paoli +14 more
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Human alphacoronavirus replication and innate immune induction in airway culture systems [PDF]
mBioCompared with lethal betacoronaviruses, there is limited knowledge of how human alphacoronaviruses HCoV-NL63 (NL63) and HCoV-229E (229E) interact with host innate immune responses.
Alejandra Fausto +13 more
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Detection and genetic characterization of alphacoronaviruses in co-roosting bat species, southeastern Kenya. [PDF]
PLoS Neglected Tropical DiseasesBats are associated with some of the most significant and virulent emerging zoonoses globally, yet research and surveillance of bat pathogens remains limited across parts of the world.
Joseph G Ogola +13 more
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Genome-scale CRISPR screen identifies TMEM198 driving double membrane vesicle formation in swine alphacoronavirus and murine betacoronavirus infected cells. [PDF]
PLoS PathogensCOVID-19 pandemic caused by the SARS-CoV-2 which is well-publicized cross-species transmissibility. SARS-CoV-2 belongs to genus Betacoronavirus, several pathogenic alphacoronaviruses have shown similar patterns of emergence.
Lei Shi +9 more
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Detection of avian, murine, bovine, shrew, and bat coronaviruses in wild mammals from Mexico [PDF]
Virology JournalCoronaviruses infect a wide range of animal and human hosts. Some human coronaviruses, such as SARS-CoV, MERS-CoV, and SARS-CoV-2, originated in animals, with bats often serving as ancestral hosts.
Jocelyn Medina-Gudiño +4 more
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Dispersal history of Miniopterus fuliginosus bats and their associated viruses in east Asia.
PLoS ONE, 2021 In this study, we examined the role of the eastern bent-winged bat (Miniopterus fuliginosus) in the dispersion of bat adenovirus and bat alphacoronavirus in east Asia, considering their gene flows and divergence times (based on deep-sequencing data ...
Thachawech Kimprasit +21 more
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