A case of Takotsubo syndrome with polymorphic ventricular tachycardia and shark fin electrocardiogram developed during hospitalization for occlusive arterial disease of the lower extremities. [PDF]
Fujiwara M, Ito H, Yamada H, Soeki T.
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Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Learning. [PDF]
Xiao S+12 more
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ERECTILE RESPONSE TO TRANSURETHRAL ALPROSTADIL, PRAZOSIN AND ALPROSTADIL-PRAZOSIN COMBINATIONS
Journal of Urology, 1998Transurethral alprostadil has been shown to be efficacious in many men with erectile dysfunction. We compared transurethral alprostadil and prazosin alone, and in combination to treat this disorder.In this double-blind, placebo controlled study the erectile responses to transurethral alprostadil, prazosin and alprostadil-prazosin combinations were ...
Neil Gesundheit+13 more
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Alprostadil for the treatment of impotence
Expert Opinion on Pharmacotherapy, 2013Erectile dysfunction (ED) affects over 150 million men worldwide. Oral phosphodiesterase-5 (PDE5) inhibitors are currently used as a first-line therapy and a second-line therapy with either intracavernosal (Caverject) or intraurethral (MUSE) alprostadil is required for a few men who show poor response or intolerance to PDE5 inhibitors.This article ...
Vishwanath Hanchanale, Ian Eardley
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Intra-arterial Alprostadil for Nonatherosclerotic Vasculopathy [PDF]
A 33-year-old man with a nonatherosclerotic vasculopathy of undetermined origin had progressive occlusive disease of the lower limb vessels. The resultant severe rest pain and ischemic ulceration of his foot were inoperable and unresponsive to conventional drug therapy.
Peter N. Madras+3 more
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Evaluation of Inhaled Alprostadil in Hospitalized Adult Patients
Annals of Pharmacotherapy, 2021Background: Intermittent inhaled alprostadil (iPGE1) may be a viable alternative to inhaled nitric oxide or epoprostenol for management of right ventricular failure, pulmonary hypertension (pHTN) or acute respiratory distress syndrome (ARDS). However, limited evidence exists regarding iPGE1 use in adults, ideal dosing strategies, or optimal use cases ...
Hangil Seo+3 more
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Optimizing the therapeutic approach of transurethral alprostadil
BJU International, 2000Objective To investigate the efficacy and safety of two different starting doses of transurethral alprostadil (250 µg and 500 µg, MUSE®, Vivus Inc., Menlo Park, CA, USA, and Astra Läkemedel AB, Södertälje, Sweden) and the need for dose titration in a general population with erectile dysfunction.
P. Ekman+3 more
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Alprostadil: An Effective Antiplatelet Agent for Calves
Artificial Organs, 1993Abstract:Aspirin and other nonsteroidal, antiinflammatory drugs inhibit human platelets, but their effect as an antiplatelet agent on bovine platelets is not certain. Since calves are used for cardiovascular implant research, need exists for an effective antiplatelet agent for this animal model.
Gregory L. Burns+3 more
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Alprostadil for erectile impotence
Drug and Therapeutics Bulletin, 1995A preparation of alprostadil (prostaglandin E1) plus syringe and diluent (Caverject - Upjohn) has recently been licensed in the UK for the treatment of erectile impotence by injection into the corpus cavernosum. How does it compare with papaverine, which, though unlicensed for this indication, has been the mainstay of drug treatment for impotence?
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A Cost Analysis of Alprostadil in Liver Transplantation
PharmacoEconomics, 1996Alprostadil (prostaglandin E1) administration to liver transplant recipients has been shown to result in a significant reduction in the duration of hospital admission for transplantation, and in the need for re-operations (other than re-transplants) and renal support.
I. Douglas McLaren+5 more
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