Results 71 to 80 of about 1,144,628 (153)
Abstract Acquired hypothalamic obesity (aHO) is characterized by rapid and persistent weight gain resulting from structural or functional damage to the hypothalamus, typically accompanied by neuroendocrine dysfunction. While aHO is well described in the context of hypothalamic or suprasellar tumors, particularly craniopharyngioma, little is known about
Julian Witte +5 more
wiley +1 more source
ABSTRACT This systematic review examined the etiologic association between physical activity (PA) and indicators of childhood overweight/obesity (OV/OB) and metabolically unhealthy obesity (MUO) risk. Original peer‐reviewed English reports published between January 01, 2013, and June 30, 2024, were retrieved from MEDLINE and Scopus.
Michael Georgoulis +9 more
wiley +1 more source
Novel Alu retrotransposon insertion leading to Alström syndrome.
Alström syndrome is a clinically complex disorder characterized by childhood retinal degeneration leading to blindness, sensorineural hearing loss, obesity, type 2 diabetes mellitus, cardiomyopathy, systemic fibrosis, and pulmonary, hepatic, and renal ...
Taşkesen, Mustafa +6 more
core +1 more source
Diffuse left ventricular interstitial fibrosis is associated with sub-clinical myocardial dysfunction in Alström Syndrome: an observational study [PDF]
BACKGROUND: Alström syndrome is a rare inherited ciliopathy with progressive multisystem involvement. Dilated cardiomyopathy is common in infancy and recurs or presents de novo in adults with high rates of premature cardiovascular death. Although Alström
Edwards, Nicola C. +15 more
core +1 more source
MRI brain revealing features consistent with central diabetes insipidus (Figure A), pontine atrophy (Figure B), and bilateral optic nerve atrophy (Figure C) in a young, non‐autoimmune diabetic patient: imaging clue to Wolfram syndrome. ABSTRACT Wolfram syndrome is a rare autosomal recessive disorder characterized by diabetes insipidus, diabetes ...
Sushrut Ingawale +4 more
wiley +1 more source
Six Years of Genetic Diagnosis of Severe Early‐Onset Obesity in a French Cohort
ABSTRACT Objective Obesity is a multifactorial disease with a strong genetic component. It is imperative to enhance the identification of genetic variations in their early and severe manifestations in order to facilitate the development of personalized therapeutic strategies, informed clinical care, and the facilitation of genetic counseling.
M. Rama +12 more
wiley +1 more source
Nyheter 2020 - rapport 2 : dagens medieföretag - morgondagens affärsidé
Innehåll: Börje Alström; På väg mot samverkan Börje Alström; Medieföretag eller kunskapsföretag Lowe Hedman; Medieföretag utan strategier? Asta Cepaite; Den föreställda framtiden Mikael Gulliksson; Ladsortsjournalister i nyhetsflödet Börje Alström; En ...
core +3 more sources
To systematically identify risk medications for migraine and its subtypes, we integrated GWAS data for 23 medications with GWASs of migraine and its subtypes to conduct causal inference. We then combined plasma eQTLs with drug‐target databases to map putative targets of the risk medications and validated causal relationships using colocalization and ...
Nan Wang +9 more
wiley +1 more source
Histopathology of the Human Inner Ear in Alström\u27s Syndrome.
Alström\u27s syndrome is an autosomal recessive syndromic genetic disorder caused by mutations in the ALMS1 gene. Sensorineural hearing loss occurs in greater than 85% of patients.
Bronson, Roderick T +2 more
core +1 more source
Recent research has ignited a renewed interest in Ceratozamia cycads, unveiling their remarkable diversity. While previous studies primarily focused on morphology, this investigation employs a multidisciplinary approach, integrating phylogenetics, morphology, and ecological niches. Our methods identify seven distinct lineages as separate species.
Anwar Medina‐Villarreal +2 more
wiley +1 more source

