Results 121 to 130 of about 736,156 (268)

Investigating Clinical Factors Influencing Pulmonary Fibrosis in Acute Diquat Poisoning

open access: yesInternational Journal of General Medicine
Meili Xu,1,2 Hongliu Chen,1,2 Jianjing Chen,3 Rongzong Ye,4 Huan Xiao,1,2 Jingwen Li,4 Chaoqian Li1,2 1Department of Emergency, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Guangxi University
Xu M   +6 more
doaj  

Twisting the End Game: How Telomere Chromatin Modifications Shape Telomere Maintenance. [PDF]

open access: yesAging Cell
Wang J   +8 more
europepmc   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Evaluación de los criterios de Centor para el manejo de la faringoamigdalitis en adultos atendidos en el servicio de urgencias

open access: yesAtención Primaria
Mariona Serrano-Bilbeny   +3 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

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