Results 161 to 170 of about 736,156 (268)

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Recension av Konrad Otto, Die Mose-Exodus-Tradition

Svensk Exegetisk Årsbok
Ludvig Nyman
doaj   +1 more source

Infected splenic artery pseudoaneurysm within a complex splenic cystic lesion: CT angiography pitfalls and surgical correlation. [PDF]

Radiol Case Rep
Amara R, Chyabri N, Mouna N, Deflaoui T, Aabalou M, Ziani H, Nasri S, Skiker I.   +7 more
europepmc   +1 more source

Findings from the ALT Annual Survey 2020 [PDF]

, 2021
Deepwell, Maren, Hawksey, Martin
core  

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

The "salted pretzel" sign: A radiological indication of a calcified amorphous tumor as a rare cause of embolic stroke. [PDF]

Radiol Case Rep
Herm H, Borgmann T, Berger M, Pels HJ.
europepmc   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Pediatric emergency department point-of-care ultrasound diagnosis of unprovoked iliofemoral deep vein thrombosis in an adolescent: A case report. [PDF]

Radiol Case Rep
Elosiuba E, McCourt E, Toko R, Udo SI, Vella A, Chukwuma Chukwuma L, Yarfoh KB, Nwatuzor C.   +7 more
europepmc   +1 more source

Structural Control Over Bicontinuous Emulsions from Solvent‐Transfer Induced Phase Separation Through Nanoparticle Loading

Advanced Science, EarlyView.
The nanoparticle loading enables effective control over the liquid domain size in bicontinuous interfacially jammed emulsion gels (bijels) produced through solvent‐transfer induced phase separation (STrIPS). The relationship between the nanoparticle loading and domain size profiles in STrIPS bijels is resolved through confocal microscopy and explained ...
Jesse M. Steenhoff, Martin F. Haase
wiley   +1 more source

Optimisation of metabolic dysfunction-associated steatotic liver disease (MASLD) screening algorithm for resource-poor settings using machine learning. [PDF]

PLoS One
Mettananda C, Sivasumithran K, Ranaweera L, Madhubhashini A, Ranawaka C, Pathmeswaran A, Dassanayake A.   +6 more
europepmc   +1 more source