Results 21 to 30 of about 1,545,190 (285)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Association between early sitting and functional mobility recovery after hip-fracture surgery in older patients: a prospective cohort study

open access: yesBMC Geriatrics
Background Hip fractures significantly impact older adults, leading to compromised mobility and various adverse outcomes. The importance of early post-surgery mobilization in regaining pre-fracture levels of mobility is recognized, but lacks standardized
Clarissa Catalano-Nadakhovskaia   +5 more
doaj   +1 more source

Causes analysis of blood donor deferral in 20 domestic blood centers

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the main causes of blood donor deferral in domestic blood center. Methods The causes of donor deferral were classified into 12 categories as previous medical history, drug use, alcohol consumption, menstrual period, underweight ...
Dongyan ZHAO   +20 more
doaj   +1 more source

Alte Herren/Alte Meister

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften, 1993
The paper discusses some aspects of autobiographical documents written by historians. Out of this genre which was named ego-histoire in France a collection of texts representing life stories of Austrian scholars older than 70 has been taken as an example for analysis. These texts allow to give first informations concerning the social composition of the
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Maths Apps index #maths4us Project Report [PDF]

open access: yes, 2013
This report provides an overview of the Maths Apps index project led by the Association for Learning Technology (ALT) as part of the maths4us initiative during 2012 ...
ALT, ALT
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

A note on the probability of generating alternating or symmetric groups [PDF]

open access: yes, 2008
We improve on recent estimates for the probability of generating the alternating and symmetric groups $\mathrm{Alt}(n)$ and $\mathrm{Sym}(n)$. In particular we find the sharp lower bound, if the probability is given by a quadratic in $n^{-1}$. This leads
Luke Morgan   +6 more
core   +4 more sources

Development and Research of Working Parts of Joint Cutting Machines with Cycloidal Motion

open access: yesCommunications
The development of a country's economy largely depends on the pace and efficiency of construction work, which, in turn, is determined by the extent to which innovative technologies and techniques are used.
Yerbol Kaliyev   +6 more
doaj   +1 more source

Research in Learning Technology - Info card [PDF]

open access: yes, 2011
Information regarding the transition of Research in Learning Technology to an Open Access ...
ALT, ALT
core  

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