Results 91 to 100 of about 57,214 (313)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
LA ROUMANIE EUROPÉENNE, ENTRE LE PLEONASME ET L’OXYMORON [PDF]
EUROPEAN ROMANIA, BETWEEN PLEONASM AND OXYMORON Trivial approaches, so frequent, to „European Romania” oblige this syntagm to alternate its status between pleonasm and oxymoron. Both should be rejected.
Acad. Solomon MARCUS
doaj
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Political Alterity in Pathé’s French and British Newsreel Coverage of the May 1968 Events in Paris
This article analyzes the use of alterity in Pathé’s British and French newsreels depicting the May 1968 events in Paris. It argues that items from both newsreels construct the viewers’ country as a center of civilized democracy, using various figures of
Tom Clucas
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
From Dog Alterity to Canine Sublime: A Cross-Century Reading of Victorian Fiction
From Charles Dickens to Joseph Conrad dogs are omnipresent in Victorian novels. Many recent critical works have investigated the part they play, either within the confines of specific novels or against the enlarged context of Victorian culture. Reversing
Georges Letissier
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Blaise Cendrars : Cabotage et traversées
Cendrars’ carefully constructed self-portrait as a poet vagabond was more successful than the image of the mystical recluse he replaced it with in the 1940s.
Marie-Paule Berranger
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source

