Results 91 to 100 of about 57,547 (311)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
, 2005 With the considerable help of Derrida, aptly aided by Mandela, this paper advances an idea of justice as integral to law. Thence, by way of an homology with such justice, access also is shown to be integral to law. What impels the overall argument is the
Fitzpatrick, Peter
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Litterature et multiculturalite: une approche comparative de l’œuvre de Panait Istrati (Roumanie – France) et de Sait Faik (Turquie) [PDF]
Diversitate si Identitate Culturala in Europa, 2018 Panait Istrati (1884-1935), a Romanian francophone author established in France, and Sait Faik Abasıyanık (1906-1954), a Turkish writer less known to the francophone public although he is one of the great figures of contemporary literature in his country,
Xavier LUFFIN
doaj
Against anthropocentrism: the destruction of the built environment as a distinct form of political violence [PDF]
, 2006 No description ...
Coward, Martin
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The King's many bodies: the self-deconstruction of law's hierarchy [PDF]
, 2006 The article connects two strands of the recent sociolegal debate: (1) the empirical discovery of new forms of spontaneous law in die Course of globalization, and (2) the emergence of deconstructive theories of law that undermine the law's hierarchy.
Teubner, Gunther
core
The Local and the Global: Hokusai's Great Wave in Contemporary Product Design [PDF]
, 2012 This article examines the impact and significance of Hokusai’s so-called The Great Wave in contemporary product promotion and design. Arguably Japan’s first global brand, this influential 19th-century woodcut has been widely adopted to style and ...
Guth, Christine
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source