Results 91 to 100 of about 58,127 (309)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Les îles lecléziennes : mémoire et initiation
Carnets, 2015 The privileged space that an island represents is an integral part of the landscapes described by Le Clézio whose two novels Le Chercheur d'or and La quarantaine express the very essence of that space in order to convey its symbolic significance ...
Bernadette Rey Mimoso‑Ruiz
doaj +1 more source
Time in the ontology of Cornelius Castoriadis [PDF]
, 2017 We can locate the problematic of time within three philosophical questions, which respectively designate three central areas of philosophical reflection and contemplation. These are: 1) The ontological question, i.e.
Schismenos, Alexandros
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
REPRESENTATIONS OF ALTERITY [PDF]
AnadissLa connaissance du Soi se perfectionne à travers la connaissance de l’Autre. Le Soi se reflète et se reconnaît dans l’Autre, soit par identification, soit par différenciation.
Porfirie PESCARU
doaj
Lost Confidence and Human Capability: A Hermeneutic Phenomenology of the Gendered, yet Capable Subject [PDF]
, 2014 In this contribution to Text Matters, I would like to introduce gender into my feminist response to Paul Ricoeur’s hermeneutic phenomenology of the capable subject.
Anderson, Pamela Sue
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
‘“Be vewy vewy quiet. We’re hunting Wippers.” A Barthesian analysis of the construction of fact and fiction in Alan Moore and Eddie Campbell’s From Hell [PDF]
, 2010 “I made it up and it all came true anyway” says the pseudo-psychic Mr Lees in the prologue to From Hell. However, it seems that this statement applies equally to the Jack the Ripper saga as a whole, whose contradictory stories and elements have been ...
Round, Julia
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source