Results 121 to 130 of about 57,214 (313)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Le roumain, le fraçais et le latin dans une grammaire roumaine du XIXème siècle [PDF]
Diversitate si Identitate Culturala in EuropaThis study aims to trace the linguistic thinking of the author of a Romanian language textbook, used as a “Romanian as a second language” coursebook. The novelty lies in the fact that the work we have studied is the first of its kind in the history of ...
Roxana-Magdalena BÂRLEA
doaj
O sujeito em contextos de uso e desenvolvimento de softwares
Psicologia: Teoria e PesquisaEste artigo discute a questão do sujeito em psicologia, tomando como cenário as práticas contemporâneas de uso de artefatos digitais, e o contexto menos observado dos ambientes de desenvolvimento de softwares.
Luciano Meira, Flávia Peres
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Bohdan Boichuk’s Childhood Reveries: A Migrant’s Nostalgia, or, Documenting Pain in Poetry [PDF]
, 2018 This paper examines Bohdan Boichuk’s poetry by looking into the role his childhood memories played in forming his poetic imagination.
Rewakowicz, Maria G.
core
Keeping it Real: Encountering Mixed Reality in igloo’s SwanQuake: House
, 2012 This paper employs the writings of early twentieth-century phenomenologists to examine physical/virtual dualism a century later. It considers the nature of embodied experience in mixed reality environments through an analysis of the author’s encounter ...
Popat, SH
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Somatics and phenomenological psychopathology: a mental health proposal. [PDF]
Theor Med Bioeth, 2023 Sánchez Sánchez C.
europepmc +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source