Results 161 to 170 of about 2,144 (261)

Apathy and Functional Status in Early-Stage Huntington's Disease. [PDF]

J Neuropsychiatry Clin Neurosci
Gibson JS, Hay KR, Claassen DO, McDonell KE, Brown AE, Wynn A, Jiang J, Isaacs DA.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Beyond Tokenism: Making Lived Experience Leadership Visible in Co-Produced Research Authorship. [PDF]

Health Expect
Randal P, Heinz S.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Bibliotherapy and Schizophrenia: A Stanghellinian Perspective.

Psychopathology
Delcourt F, Englebert J, Pachoud B.
europepmc   +1 more source

Ethical reflections in legal medicine and forensic medical expertise: looking beyond the norm. [PDF]

Rev Bras Med Trab
de Almeida G.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin-Sensitive Magnetic Resonance Imaging and ¹⁸F-Fluorodopa-Positron Emission Tomography. [PDF]

Mov Disord
Trujillo P, O'Rourke KR, Roman OC, Song AK, Hett K, Cooper A, Black BK, Donahue MJ, Shibao CA, Biaggioni I, Claassen DO.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The <i>in-related self</i>: reclaiming <i>Paarung</i> in critical phenomenological psychopathology. [PDF]

Front Psychol
Billwiller E.
europepmc   +1 more source