Results 41 to 50 of about 41,564 (302)

New Perspectives On Automatic And Morphophonological Alternations: Harmonic Processes In Two Peninsular Varieties Of Spanish

open access: yesBorealis: An International Journal of Hispanic Linguistics, 2018
The present study investigated vowel harmony (VH) in two varieties of Peninsular Spanish - Eastern Andalusian and Montañes. Despite both varieties exhibiting VH, the triggers and targets for each variety result in metaphonic alternations that are quite ...
Farrah Neumann, Matthew Kanwit
doaj   +1 more source

Alternators of a right alternative algebra [PDF]

open access: yesTransactions of the American Mathematical Society, 1978
We show that in any right alternative algebra, the additive span of the alternators is nearly an ideal. We give an easy test to use to determine if a given set of additional identities will imply that the span of the alternators is an ideal. We apply our technique to the class of right alternative algebras satisfying the condition
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Segmental alternations and metrical theory [PDF]

open access: yes, 2009
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2009.Includes bibliographical references (p. 263-268).This dissertation focuses on phonological alternations that are influenced or constrained by word-internal ...
Vaysman, Olga
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The lowering of high vowels before [r] in Latin

open access: yesPapers in Historical Phonology, 2020
This paper discusses a putative sound change in the early history of Latin and synchronic alternations apparently related to it. The lowering of short high vowels before the rhotic is problematic on several counts; so much so that serious doubt has been ...
András Cser
doaj   +1 more source

Concerning Inflection Classes in Livonian; pp. 12-26 [PDF]

open access: yesLinguistica Uralica, 2012
Livonian has among the Finnic languages characteristically the ­greatest variety of optional inflectional ending variants and the most complicated system of morphophonological alternations.
Tiit-Rein Viitso
doaj   +1 more source

Alternating, private alternating, and quantum alternating realtime automata

open access: yesLogical Methods in Computer Science, 2019
We present new results on realtime alternating, private alternating, and quantum alternating automaton models. Firstly, we show that the emptiness problem for alternating one-counter automata on unary alphabets is undecidable. Then, we present two equivalent definitions of realtime private alternating finite automata (PAFAs). We show that the emptiness
Gökalp Demirci   +4 more
openaire   +4 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The relation between phones and phonemes on examples from Pāli

open access: yesLinguistica Brunensia, 2013
The issue of the paper is, first, to describe the concept of an allophonic number, second, to confront the allophony both in Vedic and in Pāli, and third, to express different allophony in both languages with the use of allophonic numbers.
Ondřej Šefčík
doaj  

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