Results 51 to 60 of about 10,778,845 (284)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield+3 more
wiley +1 more source
Alternative Theories of CP violation [PDF]
Recent improvements to the limit of Delta M_{B_s} imply that pure superweak theories, while not excluded, no longer provide a good fit to the data. A class of general superweak theories is introduced in which all flavor changing interactions are governed
Achille Stocchi+4 more
core +3 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Alternate current machinery — Induction alternators [PDF]
In the following pages it is proposed to discuss some of the elementary phenomena found while studying the performance of alternators excited by alternating currents. In a second paper the writer intends to deal with the practical application of the principles here described.
Stanley, W.-M., Faccioli, G.
openaire +3 more sources
An alternative regional strategy [PDF]
Regions, this extract suggests, cannot bring about regional inequality without significant national level action. The key, it is claimed, is a ‘national commitment to decentre the economy’.
Amin, Ash, Massey, Doreen, Thrift, Nigel
core
Alternative to Domain Wall Fermions [PDF]
An alternative to commonly used domain wall fermions is presented. Some rigorous bounds on the condition number of the associated linear problem are derived.
Avron+16 more
core +1 more source
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
The Indications for, and Technique of, Cæsarean Section and its Alternatives, in Women with Contracted Pelves, Who Have Been Long in Labour and Exposed to Septic Infection [PDF]
Ernest H. Shaw
openalex +3 more sources
Variations on an American dream: alternative homeownership models [PDF]
With homeownership central to the national economy and U.S. housing policy, the drop in homeownership rates could have long-term negative consequences.
Erin Graves
core