Results 81 to 90 of about 4,794,911 (282)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Alternative dispute resolution in Islamic banking and finance

open access: yes, 2020
Islamic banking and finance is relatively a new component in the contemporary financial industry and growing fast across the globe. Consequently, like in any other area of business, occurrence of disputes that arise among stakeholders is unavoidable and ...
Nafees, Seeni Mohamed   +1 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

MEDIASI SEBAGAI ALTERNATIF PENYELESAIAN SENGKETA PERBANKAN

open access: yesProgresif, 2018
The more banks offer a number of products to the public, the possibility of a dispute between banks and customers is increasingly wide open as well. The existence of the customer service department in the bank is more than just a small talk.
Reko Dwi Salfutra
doaj   +1 more source

Dispute review boards in the context of Malaysian construction industry [PDF]

open access: yes, 2011
Every project may bound to have disagreement. The construction industry has been on the forefront of the alternative dispute resolution movement. The current trend is to look for methods of resolving disputes other than traditional processes (such as ...
Talib, Rozilah
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

ANALISIS PERJANJIAN KERJASAMA DAN POLA PERBANDINGAN PENYELESAIAN SENGKETADI LUAR PENGADILAN

open access: yesJurnal Hukum Volkgeist, 2019
The contract or agreement is rapidly growing at this time as the consequence logical from the development cooperation business people business. Many business cooperation carried out by businessmen in the form of a contract or written agreement.
safrin salam
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Alternative Dispute Resolution as a form of protection of civil rights, freedoms and interests

open access: yesПроблеми Законності, 2016
The article is devoted to the problems of alternative civil dispute resolution and understanding of this phenomenon in western legal tradition and through the national paradigm of forms of protection of civil rights, freedoms and interests.
Олег Степанович Ткачук
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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