Results 41 to 50 of about 311,957 (305)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Connection between Wage Growth and Social Security's Financial Condition [PDF]
The conventional view that faster wage growth would improve Social Security's financial condition rests on several measures of the program's finances that the Social Security trustees emphasize in their annual reports.
Jagadeesh Gokhale
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
An alternative to the necropolis in an overpopulated environment
The need for rational use of land resources within urban development suggests the possibility of creating a necropolis, an alternative to the traditional forms of existing cemeteries (in Khabarovsk), which is a memorial complex “Garden of Memories ...
Ирина Гареева +2 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Alternative modes of financing [PDF]
Οι χρηματοπιστωτικές αγορές είθισται να καθοδηγούνται από τη διαθέσιμη πληροφορία που κατέχουν οι επενδυτές. Εάν οι αγορές ήταν απολύτως αποτελεσματικές, οι επενδυτές δεν θα είχαν κίνητρο να ξοδεύουν χρήματα ή χρόνο για να συλλέξουν πληροφορίες για τα χρηματοοικονομικά προϊόντα, διότι σε αυτή την περίπτωση οι πληροφορίες θα αποτυπώνονταν άμεσα στις ...
openaire +1 more source
Credit cards: facts and theories [PDF]
We use data from several waves of the Survey of Consumer Finances to document credit and debit card ownership and use across US demographic groups. We then present recent theoretical and empirical contributions to the study of credit and debit card ...
Bertaut, Carol C., Haliassos, Michael
core +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Islamic finances: the way to diversify the economics of Kazakhstan
Most countries see Islamic finance as an alternative system to the existing traditional one. Because its stability during the financial crisis showed its reliability.
S. Oserbaiuly, Zh. Tekebay
doaj

