Results 41 to 50 of about 3,107,449 (241)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Review on progress in magnetic heterogeneous-based catalysts for biodiesel production
Journal of Engineering and Applied ScienceTo combat climate change and the issues associated with fossil fuels, we must transit to bio-renewable energy sources, such as biofuel, which is obtained by transesterification of triglycerides.
Ariprasanth Ramalingam +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The Importance of Alternative Drive Vehicles in Road Transport in Poland and the European Union
Logi, 2021 The development of electromobility in Poland and the whole world is an inevitable process. Every year, electric vehicles and vehicles powered by renewable fuels become more and more popular.
Frej Damian +2 more
doaj +1 more source
Qualification of Alternative Jet Fuels
Frontiers in Energy Research, 2021 Historically, the commercial aviation industry has relied on a very limited number of well-proven, conventional fuels for certification and operation of aircraft and engines.
Mark A. Rumizen
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Exotic glycerol dehydrogenase expressing Escherichia coli increases yield of 2,3-butanediol
Bioresources and Bioprocessing, 2018 Background The thriving of biodiesel industry has led to produce 10% (v/v) crude glycerol, thus creating an overflow problem. Biofuel production is restricted by Escherichia coli due to its toxicity to bacterial cells.
Md. Shafiqur Rahman +2 more
doaj +1 more source
, 2017 Alternative fuel for aviation has been the centre of serious focus for the last decade, owing mostly to the challenges posed by the price of conventional petroleum fuel, energy security and environmental concerns.
Craig R. Davison +4 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source