Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Another world is possible? – Climate movements’ bounded politicization between science and politics
Frontiers in Political ScienceHow we have come to think about climate futures has predominantly been shaped by science- and expert-driven assessments. As research turns to the role of future visions as a driver of social change and overcoming political gridlock, political struggles ...
Christopher N. Pavenstädt
doaj +1 more source
Commodity investments: opportunities for Indian institutional investors [PDF]
An attempt has been made to establish the fact that by investing in commodities or it alternative channels, institutional investors like banks can not only compensate for the lower risk-free returns in their major chunk of investments in Government ...
Mukherjee, Dr. Kedar nath
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Forecasting Commodity Prices Using Futures: The Case of Copper
RisksThis paper analyzes three forecasting methods for commodity spot prices and applies them to copper prices. The first method uses futures prices from either LME or COMEX. The second method uses analysts’ consensus expectations, reported by Bloomberg.
Gonzalo Cortazar +2 more
doaj +1 more source
Alternative Futures for the EU-Turkey Accession Negotiations [PDF]
Central European Journal of International & Security Studies, 2013 This work proposes a simple two-period interaction model to study EU-Turkey accession negotiations. Turkey perceives the EU as composed of two distinct groups with respect to its accession: traditional supporters and objectors.
Serdar Ş. Güner
doaj
On the spot-futures no-arbitrage relations in commodity markets
, 2018 In commodity markets the convergence of futures towards spot prices, at the expiration of the contract, is usually justified by no-arbitrage arguments.
Aïd, René +2 more
core
A Second Look at the 2007-08 Food Price Crisis: Considering the Impact of Endogenous Dynamics on Food Prices [PDF]
, 2012 This paper offers an alternative to the conventional explanation of the 2007-08 food price crisis in terms of escalating demand or dwindling supply.
Russi, L.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source