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Carcinogenesis: An Alternative Hypothesis Comparing Mutagenic Versus Metabolic Models [PDF]

open access: yesBiology
Carcinogenesis, while traditionally attributed to the accumulation of driver mutations in genes regulating cell proliferation and apoptosis, may also be explored as a consequence of fundamental metabolic reprogramming, an idea catalyzed by the Warburg ...
Albert Alhatem   +4 more
doaj   +2 more sources

Alternative Hypothesis Testing Procedures for DIMTEST. [PDF]

open access: yesAppl Psychol Meas, 2015
Many commonly used item response models make the unidimensionality assumption of a single latent trait underlying the response data. The validity of this assumption needs to be tested before these models can be applied. One option is to use Stout’s non-parametric hypothesis test of essential unidimensionality, which is operationalized in the DIMTEST ...
Kieftenbeld V, Nandakumar R.
europepmc   +4 more sources

First- and Second-Order Hypothesis Testing for Mixed Memoryless Sources

open access: yesEntropy, 2018
The first- and second-order optimum achievable exponents in the simple hypothesis testing problem are investigated. The optimum achievable exponent for type II error probability, under the constraint that the type I error probability is allowed ...
Te Sun Han, Ryo Nomura
doaj   +4 more sources

There are no alternative hypotheses in tests of null hypotheses [PDF]

open access: yesFrontiers in Psychology
Null hypothesis statistical testing (NHST) is typically taught by first posing a null hypothesis and an alternative hypothesis. This conception is sadly erroneous as there is no alternative hypothesis in the NHST.
Denis Cousineau
doaj   +2 more sources

An Alternative Hypothesis Testing Strategy for Secondary Phenotype Data in Case-Control Genetic Association Studies [PDF]

open access: yesFrontiers in Genetics, 2014
Motivated by the challenges associated with accounting for the ascertainment when analyzing secondary phenotypes that are correlated with case-control status, Lin and Zeng have proposed a method that properly reflects the case-control sampling. (Lin and
Sharon M Lutz   +2 more
doaj   +2 more sources

Introducing Alternative-Based Thresholding for Defining Functional Regions of Interest in fMRI [PDF]

open access: yesFrontiers in Neuroscience, 2017
In fMRI research, one often aims to examine activation in specific functional regions of interest (fROIs). Current statistical methods tend to localize fROIs inconsistently, focusing on avoiding detection of false activation.
Jasper Degryse   +5 more
doaj   +4 more sources

Non-causal laws: an alternative hypothesis to Armstrong’s hypothesis

open access: yesPrincipia: An International Journal of Epistemology
Non-causal laws have long been a thorn in David Armstrong’s side. This paper aims to provide a more accommodating framework for these laws within Armstrong’s metaphysics of laws of nature.
Eduardo Castro
doaj   +2 more sources

Validation of Reliability Indices during Experimental Development of a Complex Technical Series System

open access: yesAdvanced Engineering Research, 2023
Introduction. The article studies the problem of validating the specified levels of reliability during experimental development of a complex technical series system. Such tasks arise when it is required to make a decision on testing the system as part of
O. Yu. Tsarev, Yu. A. Tsarev
doaj   +1 more source

Alternative lifestyles: A plague persistence hypothesis

open access: yesEcosphere, 2023
Several explanations have been posited for how the plague bacterium (Yersinia pestis) reemerges during sylvatic cycles within the same foci over many years, and often without direct evidence of host die‐offs.
Jeffrey Wimsatt   +3 more
doaj   +1 more source

Hypothesis of the scientific research [PDF]

open access: yesUniverzitetska Misao, 2019
To clarify the hypotheses of scientific research and their role, it is first necessary to clarify the hypothesis concept. The hypothesis is called the initial and unsafe assumption, but it is, however, unlikely to be verified, based on which the first ...
Rexhep Bujari Remzi, Ali Azemi Bashkim
doaj   +1 more source

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