Results 151 to 160 of about 9,412,461 (300)

Carbon-Fibre-Reinforced SiC Composite (C/SiSiC) as an Alternative Material for Endoprosthesis: Fabrication, Mechanical and In-Vitro Biological Properties. [PDF]

Materials (Basel), 2018
Reichert A, Seidenstuecker M, Gadow R, Mayr HO, Suedkamp NP, Latorre SH, Weichand P, Bernstein A.   +7 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Alternative and Activist Media

A study of the alternative media that can be found outside the mainstream mass media.Intro -- Illustrations -- Acknowledgements -- Preface -- 1 Who needs an alternative?
Waltz, Mitzi.
core  

PETG as an Alternative Material for the Production of Drone Spare Parts. [PDF]

Polymers (Basel)
Baltić MZ, Vasić MR, Vorkapić MD, Bajić DM, Piteľ J, Svoboda P, Vencl A.   +6 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Synthesis, physical characteristics, and biocompatibility test of chitosan-alginate-fucoidan scaffold as an alternative material for alveolar bone substitution. [PDF]

BMC Oral Health
Hamrun N, Herdianto N, Gustiono D, Oktawati S, Kamil K, Marlina E, Ibriana I, Nurfaizah T, Arif AR, Azalia F, Hasanuddin H.   +10 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Report of the Alternative Fuel Vehicle Infrastructure Working Group

, 2010
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Apr.

core  

Vaginal host response to polycarbonate urethane, an alternative material for the repair of pelvic organ prolapse. [PDF]

Acta Biomater
Knight K, Breedlove S, Obisesan T, Egnot M, Daneshdoost N, King G, Meyn L, Gall K, Moalli P.   +8 more
europepmc   +1 more source