Results 161 to 170 of about 9,463,612 (394)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Alternative media in a digital era: Comparing news and information use among activists in the United States and Latin America

Communication & Society (Formerly Comunicación y Sociedad), 2013
As activists increasingly use the Internet to bypass traditional media gatekeepers, disseminate their own messages, and mobilize protests, this study explores how activists in the United States and Latin America view activism in relation to mainstream ...
Summer Harlow, Dustin Harp
doaj  

Democracy and digital disintegration: Platforms, actors, citizens

Nordicom Review
The digital transformations of contemporary media systems have had severe consequences for democracy and public debates. This introductory article addresses key challenges of what we refer to as varieties of “digital disintegration” within democratic ...
Widholm Andreas, Ekman Mattias
doaj   +1 more source

Communication perspectives on social networking and citizen journalism challenges to traditional newspapers [PDF]

Communication perspectives are presented on the challenges posed to traditional newspapers by social media and citizen journalism, with special reference to the United States.
Katz, James E.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Counter Publicity of Kurdish Women Journals: ROZA as an Alternative Media Exam [PDF]

, 2015
Assist. Prof. Dr. Nevin Yıldız Tahincioğlu, Nalan Ova   +1 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

How French alternative media channels on YouTube portray the government and mainstream media on YouTube

Frontiers in Communication
In an increasingly fragmented media landscape, YouTube has become a pivotal platform for alternative media channels that challenge mainstream media and governmental narratives.
Maud Reveilhac, Camille Nchakga
doaj   +1 more source

Alternative and Mainstream Media

, 2011
Alternative media have historically been a central force in social change. Kenix argues, however, that they do not uniformly subvert the hierarchies of access that have always been fundamental to mainstream media. In fact, their journalistic norms and routines have always drawn on the professional standards of the mainstream.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source