Results 51 to 60 of about 2,965,326 (302)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Frontiers in CommunicationAlternative media is increasingly a strategic tool in environmental justice movements. One area that remains especially understudied is how marginalised women, specifically, indigenous and Dalit women, use alternative media in India to put forward their ...
Kayonaaz Kalyanwala
doaj +1 more source
Media transformation and new practices of citizenship: the example of environmental activism in South Durban [PDF]
, 2002 South African media and telecommunications have been fundamentally restructured in the last decade. Corporate unbundling and black economic empowerment have transformed the ownership of broadcasting, print media, publishing, and telecommunications; new ...
Barnett, Clive
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Processing mathematics through digital technologies: A reorganisation of student thinking? [PDF]
, 2011 This article reports on aspects of an ongoing study examining the use of digital media in mathematics education. In particular, it is concerned with how understanding evolves when mathematical tasks are engaged through digital pedagogical media in ...
Calder, Nigel Stuart
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Media capture in a democracy: the role of wealth concentration [PDF]
Since objective news coverage is vital to democracy, captured media can seriously distort collective decisions. The current paper develops a voting model where citizens are uncertain about the welfare eþects induced by alternative policy options and ...
Corneo, Giacomo
core +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
From Inside the Rhizome: Mapping the Greek Alternative Mediascape
International Journal of Communication, 2019 We use the rhizome metaphor to approach the highly elusive and contingent field of alternative media. We explore the multiplicity of alternative media practices employed by diverse social actors, critically reflecting on the rhizome’s capacity to foster
Pantelis Vatikiotis, Dimitra L. Milioni
doaj +2 more sources