Results 51 to 60 of about 8,062 (217)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
صحافة المواطن والصحافة التقليدية: بين التنافس والتكامل
The most important change, that happened in the last decade, at the level of press, was the emergence of « citizen journalism”, as a new form of non-professional journalistic practice. The special rapporteur, in charge of the protection of the freedom of
صبرينة برارمة
doaj
What is ‘alternative’ About alternative social media?
What are alternative social media (ASM)? What is it that makes social media ‘alternative’ and how can one approach their study? Rather than attempting to answer these questions in order to provide a precise and stable definition of alternative social media, this paper will offer a working definition of ASM.
Roscam Abbing, Roel, Gehl, Robert W.
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A Diagnosis of Daily News’ Framing of Anti-Mnangagwa Protests Through the Media Capture Lens
This qualitative interpretive case study investigates how Zimbabwe’s independent daily newspaper, the Daily News, reported on the 31 March 2025, anti-President Emmerson Mnangagwa protests organized by war veterans.
Takunda Maodza
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
In the last years we have witnessed an explosion of self-managed feminist publications, mainly zines but also newsletters or independent magazines. Practices of creation and diffusion are a reflection of Iberian feminisms, self-management, collective ...
Laura López Casado
doaj +1 more source

