Results 181 to 190 of about 7,589,999 (429)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

An approach to enhanced stability: Formulation and characterization of Solanum lycopersicum derived lycopene based topical emulgel

open access: yesSaudi Pharmaceutical Journal, 2018
Focus of the study was to design a novel and cost effective extraction technique for the lycopene from Lycopersicum esculentum L. fruit and to develop and characterize a stable emulgel formulation containing lycopene as an active ingredient as well as to
Muhammad Sohail   +5 more
doaj  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Alternative medicine in aquaculture [PDF]

open access: yes, 2017
Η χρήση εναλλακτικών θεραπειών στις υδατοκαλλιέργειες και γενικότερα στα παραγωγικά ζώα έχει γίνει στις ημέρες μας επιτακτική για σημαντικούς λόγους.
ATHANASSOPOULOU (ΑΘΑΝΑΣΟΠΟΥΛΟΥ Φ.), F.   +2 more
core   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Discrimination in Medical Settings and Attitudes toward Complementary and Alternative Medicine: The Role of Distrust in Conventional Providers

open access: yes, 2013
This study examines the relationship between racial/ethnic discrimination in medical settings, distrust in conventional medicine, and attitudes toward complementary and alternative medicine (CAM) among a racially/ethnically diverse sample.
Call, Kathleen T   +6 more
core  

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