Results 61 to 70 of about 7,853,320 (356)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Cathepsin K knockout protects against cardiac dysfunction in diabetic mice

Scientific Reports, 2017
Diabetes is a major risk factor for cardiovascular disease and the lysosomal cysteine protease cathepsin K plays a critical role in cardiac pathophysiology.
Rui Guo, Yinan Hua, Olivia Rogers, Travis E. Brown, Jun Ren, Sreejayan Nair   +5 more
doaj   +1 more source

Prevalence of late and long-term effects of cancer (treatment) and use of complementary and alternative medicine in Norway

BMC Complementary Medicine and Therapies, 2022
Background The increasing number of patients surviving cancer leads to more people experiencing late and long term-effects from the disease and its treatment.
Agnete E. Kristoffersen, Barbara Wider, Jorunn V. Nilsen, Mona Bjelland, Dana C. Mora, Johanna Hök Nordberg, Ann Ragnhild Broderstad, Kiwumulo Nakandi, Trine Stub   +8 more
doaj   +1 more source

Proceeding: 3rd Java International Nursing Conference 2015 “Harmony of Caring and Healing Inquiry for Holistic Nursing Practice; Enhancing Quality of Care”, Semarang, 20-21 August 2015 [PDF]

, 2015
This is the proceeding of the 3rd Java International Nursing Conference 2015 organized by School of Nursing, Faculty of Medicine, Diponegoro University, in collaboration with STIKES Kendal.
Nurmalia (Editor), D, Padmasari (Editor), S, Rokhana (Editor), N, Utami (Editor), RS, Yatuni (Editor), FY   +4 more
core  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Medical Cannabis Prescription Practices and Quality of Life in Thai Patients: A Nationwide Prospective Observational Cohort Study

Medical Cannabis and Cannabinoids
Introduction: The legalization of cannabis in Thailand has renewed interest in its traditional medical use. This study aimed to explore the prescribing patterns of traditional practitioners and assess the impact of cannabis oil on patients’ quality of ...
Pramote Stienrut, Krit Pongpirul, Phanupong Phutrakool, Chatuthanai Savigamin, Pim Sermsaksasithorn, Ornpapha Chanhom, Panthakan Jeamjumrus, Pimlada Pongchaichanon, Preecha Nootim, Mala Soisamrong, Anchalee Chuthaputti, Kulthanit Wanaratna, Tewan Thaneerat   +12 more
doaj   +1 more source

Dysregulated circular RNAs and their pathological implications in knee osteoarthritis: potential novel therapeutic targets and diagnostic biomarkers

All Life, 2022
Osteoarthritis (OA) is the most common form of arthritis and a leading cause of chronic pain and disability in the elderly. However, the detailed molecular mechanisms of OA remain unclear.
Jaehee Kim
doaj   +1 more source

A Review of the Anti-diabetic Activity of Andrographis Paniculata (Burm. F.) Nees Based In-vivo Study [PDF]

, 2015
Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life.
Harimurti, S. (Sabtanti), Komalasari, T. (Titi)   +1 more
core  

Prevalence, patterns, and perceived value of complementary and alternative medicine among cancer patients: a cross-sectional, descriptive study

BMC Complementary and Alternative Medicine, 2017
BackgroundSophisticated conventional medicine (CM) has brought significant advances to cancer prevention, detection, and treatment. However, many cancer patients still turn to complementary and alternative medicine (CAM) treatment.
M. Bahall
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source