Results 81 to 90 of about 1,323,660 (313)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Qualitative systemic review of randomized controlled trials on complementary and alternative medicine treatments in fibromyalgia [PDF]

, 2009
Julia Baranowsky, Petra Klose, Frauke Musial, Winfried Häuser, Gustav Dobos, Jost Langhorst   +5 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A new official national regulations for complementary medicine practices in Saudi Arabia

Integrative Medicine Research, 2021
Tamer Aboushanab, Saad Baslom
doaj   +1 more source

P05.66 . “It’s a regular part of my schedule, just like brushing my teeth”: the perceived fit of complementary and alternative medicine among young adults [PDF]

, 2012
Fuschia M. Sirois
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

6-Paradol mitigates rotenone-induced Parkinson’s disease via shutting TNFR-1/RIPK1/RIPK3/MLKL cascade and enhancement of PPARγ/PGC-1α/TFAM axis

Future Journal of Pharmaceutical Sciences
Background Zingiber officinale rhizomes (Ginger, Zingiberaceae) are used traditionally in treating various ailments, including neurodegenerative diseases.
Alaa Sirwi, Mostafa A. Rabie, Abdulrahman E. Koshak, Dina A. I. Albadawi, Ali M. El-Halawany, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Nesrine S. El-Sayed   +8 more
doaj   +1 more source

COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM) PADA ANAK DENGAN LEUKEMIA (LITERATURE REVIEW)

, 2021
Yuniske Penyami, Ns Mardi Hartono S.Kep, M.Kes Moh. Projo Angkasa, Shinta Aprilia, Maqhviroh Nurvitasari Rohmah   +4 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Aristophanes’ Wealth: Ancient Alternative Medicine and its Modern Survival [PDF]

, 1996
N. Koutouvidis, Esther Papamichael, A Fotiadou   +2 more
openalex   +1 more source