Results 201 to 210 of about 247,846 (249)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Accurate classification and prediction of knee osteoarthritis based on Al-Biruni Earth Radius metaheuristic optimizer and LSTM classifier. [PDF]

Sci Rep
Diab AG, El-Kenawy EM, Areed NFF, Amer HM, El-Seddek M.   +4 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Understanding the Importance, Utility, and Responsible Application of the H-index in Orthopedics. [PDF]

J Orthop Case Rep
Kale S, Senthil V, Roy M, Shyam A.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Evaluation of 3D-CRT vs. VMAT for radiotherapy of whole breast with simultaneous integrated boost. [PDF]

Acta Oncol
Johansson G, Kojoj R, Surdashi S, Olin M, Fredén E, Sen P, Dahl E, Wendt C.   +7 more
europepmc   +1 more source

ExplainTS: a benchmark dataset of pretrained models and <i>post-hoc</i> explanations for time-series classification. [PDF]

Front Artif Intell
Mozolewski M, Bobek S, Nalepa GJ.
europepmc   +1 more source

Persistent cycles and network resilience: a hypernetwork-based framework for temporal graph analysis. [PDF]

Sci Rep
Li B, Abinova A, Li S.
europepmc   +1 more source

Comparative screening accuracy of the Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-Chat-R/F) for early autism spectrum disorder: a systematic review. [PDF]

Fam Med Community Health
Tsen ASF, Bantalani MA, Ab Rahim MN, Amat SZA, Mokti K.   +4 more
europepmc   +1 more source

An Investigation of Alternative Daylight Metrics

, 2020
openaire   +1 more source