Results 111 to 120 of about 2,523,009 (328)
Sexual citizenship, nationalism and biopolitics in Putin’s Russia [PDF]
, 2015 The chapter explores the articulation between sexuality and nationalism in Russia, where sexual and reproductive rights have become increasingly politicised, as evidenced by legislation restricting access to abortion (2011) and forbidding ‘gay propaganda’
Nartova, Nadya, Stella, Francesca
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The Role of Social Networks in Egypt’s January 2011Revolution
Journal of Arts & Social Sciences, 2015 This paper examines the role of the online social networks, especially Facebook, during the Egyptian revolution in January 2011. Analysis of a sample of pages shows how these networks helped people exchange information before, during and after the 18 ...
Hosni Mohamed Naser
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Social Media + Society, 2018 This article examines the creation and utilization of subversive expressions by Chinese Internet users amid heavy censorship. While these expressions may potentially lead to collective resistance, so far they have not been subjected to systematic ...
Sulafa Zidani
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Communication perspectives on social networking and citizen journalism challenges to traditional newspapers [PDF]
Communication perspectives are presented on the challenges posed to traditional newspapers by social media and citizen journalism, with special reference to the United States.
Katz, James E.
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
, 2016 The key focus of this paper revolves around the dual concepts of teachers acting as ‘digital intermediaries’ for students, pupils or marginalized persons and their ‘designing’ role in developing, maintaining and celebrating the creation of ideas ...
Mitchell, Stuart, Pelka, Bastian
core
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source