Results 121 to 130 of about 877,869 (275)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Antibiotic resistance: a rundown of a global crisis

open access: yesInfection and Drug Resistance, 2018
Bilal Aslam,1 Wei Wang,2 Muhammad Imran Arshad,3 Mohsin Khurshid,1,4 Saima Muzammil,1 Muhammad Hidayat Rasool,1 Muhammad Atif Nisar,1 Ruman Farooq Alvi,1 Muhammad Aamir Aslam,2 Muhammad Usman Qamar,1 Muhammad Khalid Farooq Salamat,5 Zulqarnain Baloch6 ...
Aslam B   +11 more
doaj  

Snake Venom Compounds: A New Frontier in the Battle Against Antibiotic-Resistant Infections

open access: yesToxins
The occurrence of antibiotic-resistant bacteria is a serious global health issue, and it emphasizes the need for novel antimicrobial agents. This review explores the potential of snake venom as another alternative strategy against antimicrobial ...
Barathan Muttiah, Alfizah Hanafiah
doaj   +1 more source

Latino Acculturative Stress Implications, Psychotherapeutic Processes, and Group Therapy [PDF]

open access: yes, 2012
The Latino population is the fastest growing ethnic minority group in the United States. Yet, Latinos do not receive adequate mental health treatment due to the lack of cultural sensitivity regarding the necessity of bilingual and bicultural staff and ...
Doucette, David W, Russell, Micah
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Carbapenem Resistance in Acinetobacter baumannii: Mechanisms, Therapeutics, and Innovations

open access: yesMicroorganisms
The global rise of carbapenem-resistant Acinetobacter baumannii (CRAB) strains poses a critical challenge to healthcare systems due to limited therapeutic options and high mortality rates, especially in intensive care settings.
Joyce de Souza   +5 more
doaj   +1 more source

The local evaluation of Knutsford’s Healthy Living Network: January 2006 – December 2006

open access: yes, 2007
This was an exploratory study designed to evaluate the Knutsford Healthy Living Network (KHLN), one of many Healthy Living Centres (HLC) in the UK. The HLC initiative aims to ensure people can achieve their optimum state of health and well-being.
Alford, Simon, Perry, Catherine
core  

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