Results 141 to 150 of about 1,094,490 (314)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Rural women in habitat services : a policy brief

open access: yes, 2011
Due to Gendered Identities and lack of requisite opportunities the level of sustained participation of women as skilled labour in habitat services is limited. With construction being the next biggest employer in the country after Agriculture, and women
Development Alternatives
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Revisiting Alternatives to the Straight of Hormuz

open access: yes, 2012
In recent weeks, the government of Iran has threatened to shut down the Strait of Hormuz amid escalating tensions with the United States and its allies.
Brito, Dagobert L.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Barefoot College : case study

open access: yes, 2011
Training has been provided in habitat services to 15,000 women in solar engineering, mechanical repair and fabrication (such as hand pump mechanics), solar cooker engineering, and masonry.
Development Alternatives
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

AMÉRICA LATINA: a luta social pelo público na crise estrutural do capital

open access: yesRevista de Políticas Públicas, 2012
This article highlights the historical importance of the new social struggle for public affairs and spaces in the countries of Latin America. It emphasizes the importance of political struggle and analyses the strategy of popular movements in Latin ...
Lucio Fernando Oliver Costilla
doaj  

Home - About - Disclaimer - Privacy