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The promise of cardiomyocyte computational models for drug safety. [PDF]
Wang L, Rodriguez B.
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New approach methodologies (NAMs) to support regulatory assessment of developmental immunotoxicity - a new PARC project. [PDF]
Smith NM +30 more
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The Validation and Acceptance of Alternatives to Animal Testing
Toxicology in Vitro, 1999Validation is the key to the regulatory status of alternative methods. A series of questions are put, to which answers are given, including the following: What is validation? What is meant by "relevance", "reliability" and "purpose"? Why and when is formal validation necessary? What comes before and after a formal validation study?
M, Balls, J H, Fentem
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Chemical & Engineering News Archive, 2007
TESTING CHEMICALS on animals for human toxicity should be greatly reduced and can potentially be eliminated in favor of experiments using cells, cell lines, or cellular components, says a National Research Council report released last week. Advances in systems biology and methods to test cells and tissues are fundamentally changing the way scientists ...
CHERYL HOGUE, JEFF JOHNSON
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TESTING CHEMICALS on animals for human toxicity should be greatly reduced and can potentially be eliminated in favor of experiments using cells, cell lines, or cellular components, says a National Research Council report released last week. Advances in systems biology and methods to test cells and tissues are fundamentally changing the way scientists ...
CHERYL HOGUE, JEFF JOHNSON
openaire +1 more source

